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Gallo, David A.; Cramer, Stefanie J.; Wong, Jessica T.; Bennett, David A. – Neuropsychologia, 2012
Alzheimer's disease (AD) can impair metacognition in addition to more basic cognitive functions like memory. However, while global metacognitive inaccuracies are well documented (i.e., low deficit awareness, or anosognosia), the evidence is mixed regarding the effects of AD on local or task-based metacognitive judgments. Here we investigated local…
Descriptors: Evidence, Cues, Alzheimers Disease, Diseases
Ries, Michele L.; McLaren, Donald G.; Bendlin, Barbara B.; Xu, Guofan; Rowley, Howard A.; Birn, Rasmus; Kastman, Erik K.; Sager, Mark A.; Asthana, Sanjay; Johnson, Sterling C. – Neuropsychologia, 2012
It is tentatively estimated that 25% of people with early Alzheimer's disease (AD) show impaired awareness of disease-related changes in their own cognition. Research examining both normative self-awareness and altered awareness resulting from brain disease or injury points to the central role of the medial prefrontal cortex (MPFC) in generating…
Descriptors: Interaction Process Analysis, Alzheimers Disease, Diseases, Rating Scales
Plancher, G.; Tirard, A.; Gyselinck, V.; Nicolas, S.; Piolino, P. – Neuropsychologia, 2012
Most neuropsychological assessments of episodic memory bear little similarity to the events that patients actually experience as memories in daily life. The first aim of this study was to use a virtual environment to characterize episodic memory profiles in an ecological fashion, which includes memory for central and perceptual details,…
Descriptors: Computer Simulation, Alzheimers Disease, Diseases, Identification
Gronholm-Nyman, Petra; Rinne, Juha O.; Laine, Matti – Neuropsychologia, 2010
We studied how subjects with mild cognitive impairment (MCI), early Alzheimer's disease (AD) and age-matched controls learned and maintained the names of unfamiliar objects that were trained with or without semantic support (object definitions). Naming performance, phonological cueing, incidental learning of the definitions and recognition of the…
Descriptors: Mild Mental Retardation, Alzheimers Disease, Memory, Semantics
Herrera, C.; Chambon, C.; Michel, B. F.; Paban, V.; Alescio-Lautier, B. – Neuropsychologia, 2012
Considering the high risk for individuals with amnestic Mild Cognitive Impairment (A-MCI) to progress towards Alzheimer's disease (AD), we investigated the efficacy of a non-pharmacological intervention, that is, cognitive training that could reduce cognitive difficulties and delay the cognitive decline. For this, we evaluated the efficacy of a…
Descriptors: Control Groups, Investigations, Intervention, Alzheimers Disease
Kim, Nam-Gyoon; Park, Jong-Hee – Neuropsychologia, 2010
Recent research has demonstrated that Alzheimer's disease (AD) affects the visual sensory pathways, producing a variety of visual deficits, including the capacity to perceive structure-from-motion (SFM). Because the sensory areas of the adult brain are known to retain a large degree of plasticity, the present study was conducted to explore whether…
Descriptors: Alzheimers Disease, Motion, Patients, Memory
Joubert, Sven; Brambati, Simona M.; Ansado, Jennyfer; Barbeau, Emmanuel J.; Felician, Olivier; Didic, Mira; Lacombe, Jacinthe; Goldstein, Rachel; Chayer, Celine; Kergoat, Marie-Jeanne – Neuropsychologia, 2010
Semantic deficits in Alzheimer's disease have been widely documented, but little is known about the integrity of semantic memory in the prodromal stage of the illness. The aims of the present study were to: (i) investigate naming abilities and semantic memory in amnestic mild cognitive impairment (aMCI), early Alzheimer's disease (AD) compared to…
Descriptors: Semantics, Alzheimers Disease, Diseases, Integrity
Julien, Camille L.; Neary, David; Snowden, Julie S. – Neuropsychologia, 2010
Arithmetic skills are generally claimed to be preserved in semantic dementia (SD), suggesting functional independence of arithmetic knowledge from other aspects of semantic memory. However, in a recent case series analysis we showed that arithmetic performance in SD is not entirely normal. The finding of a direct association between severity of…
Descriptors: Semantics, Alzheimers Disease, Patients, Memory
Hornberger, M.; Bell, B.; Graham, K. S.; Rogers, T. T. – Neuropsychologia, 2009
We employed a triadic comparison task in patients with Alzheimer's disease (AD) and healthy controls to contrast (a) multidimensional scaling (MDS) and accuracy-based assessments of semantic memory, and (b) degraded-store versus degraded-access accounts of semantic impairment in Alzheimer's disease (AD). Similar to other studies using triadic…
Descriptors: Control Groups, Animals, Semantics, Alzheimers Disease
Chang, Yu-Ling; Bondi, Mark W.; Fennema-Notestine, Christine; McEvoy, Linda K.; Hagler, Donald J., Jr.; Jacobson, Mark W.; Dale, Anders M. – Neuropsychologia, 2010
Understanding the underlying qualitative features of memory deficits in mild cognitive impairment (MCI) can provide critical information for early detection of Alzheimer's disease (AD). This study sought to investigate the utility of both learning and retention measures in (a) the diagnosis of MCI, (b) predicting progression to AD, and (c)…
Descriptors: Control Groups, Alzheimers Disease, Correlation, Verbal Learning
Colombo, Lucia; Fonti, Cristina; Stracciari, Andrea – Neuropsychologia, 2009
A group of 20 patients with probable Alzheimer disease (AD) and a control group were tested in a verb generation task, in a verb synonym task and several cognitive tests. Three types of verbs and novel verbs were presented in simple sentence frames, in two different conditions. In one condition participants were presented with the verb in the…
Descriptors: Control Groups, Semantics, Verbs, Alzheimers Disease
Villemagne, V. L.; Pike, K. E.; Darby, D.; Maruff, P.; Savage, G.; Ng, S.; Ackermann, U.; Cowie, T. F.; Currie, J.; Chan, S. G.; Jones, G.; Tochon-Danguy, H.; O'Keefe, G.; Masters, C. L.; Rowe, C. C. – Neuropsychologia, 2008
Approximately 30% of healthy persons aged over 75 years show A[beta] deposition at autopsy. It is postulated that this represents preclinical Alzheimer's disease (AD). We evaluated the relationship between A[beta] burden as assessed by PiB PET and cognitive decline in a well-characterized, non-demented, elderly cohort. PiB PET studies and…
Descriptors: Alzheimers Disease, Cognitive Tests, Older Adults, Memory