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Direct linkScerif, Gaia; Cornish, Kim; Wilding, John; Driver, Jon; Karmiloff-Smith, Annette – Neuropsychologia, 2007
Fragile X syndrome (FXS) is due to the silencing of a single X-linked gene and it is associated with striking attentional difficulties. As FXS is well characterised at the cellular level, the condition provides a unique opportunity to investigate how a genetic dysfunction can impact on the development of neurocomputational properties relevant to…
Descriptors: Genetic Disorders, Mental Retardation, Attention Control, Children
Johnson, Katherine A.; Barry, Edwina; Bellgrove, Mark A.; Cox, Marie; Kelly, Simon P.; Daibhis, Aoife; Daly, Michael; Keavey, Michelle; Watchorn, Amy; Fitzgerald, Michael; McNicholas, Fiona; Kirley, Aiveen; Robertson, Ian H.; Gill, Michael – Neuropsychologia, 2008
Increased variability in reaction time (RT) has been proposed as a cardinal feature of attention deficit hyperactivity disorder (ADHD). Increased variability during sustained attention tasks may reflect inefficient fronto-striatal and fronto-parietal circuitry; activity within these circuits is modulated by the catecholamines. A disruption to…
Descriptors: Comparative Analysis, Stimulants, Drug Therapy, Reaction Time
Wiersema, Jan R.; van der Meere, Jacob J.; Roeyers, Herbert – Neuropsychologia, 2007
The aim of the study was to investigate the developmental trajectory of error monitoring. For this purpose, children (age 7-8), young adolescents (age 13-14) and adults (age 23-24) performed a Go/No-Go task and were compared on overt reaction time (RT) performance and on event-related potentials (ERPs), thought to reflect error detection…
Descriptors: Reaction Time, Adolescents, Cognitive Processes, Brain Hemisphere Functions
