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Briggs, James F.; Olson, Brian P. – Learning & Memory, 2013
We investigated whether reexposure to an amnestic agent would reverse amnesia for extinction of learned fear similar to that of a reactivated memory. When cycloheximide (CHX) was administered immediately after a brief cue-induced memory reactivation (15 sec) and an extended extinction session (12 min) rats showed retrograde amnesia for both…
Descriptors: Memory, Models, Fear, Drug Use
Bird, Chris M.; Davies, Rachel A.; Ward, Jamie; Burgess, Neil – Learning & Memory, 2011
The influence of pre-experimental autobiographical knowledge on recognition memory was investigated using as memoranda faces that were either personally known or unknown to the participant. Under a dual process theory, such knowledge boosted both recollection- and familiarity-based recognition judgements. Under an unequal variance signal detection…
Descriptors: Familiarity, Recognition (Psychology), Autobiographies, Investigations
Theberge, Florence R. M.; Milton, Amy L.; Belin, David; Lee, Jonathan L. C.; Everitt, Barry J. – Learning & Memory, 2010
A distributed limbic-corticostriatal circuitry is implicated in cue-induced drug craving and relapse. Exposure to drug-paired cues not only precipitates relapse, but also triggers the reactivation and reconsolidation of the cue-drug memory. However, the limbic cortical-striatal circuitry underlying drug memory reconsolidation is unclear. The aim…
Descriptors: Cues, Cocaine, Symptoms (Individual Disorders), Classical Conditioning