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Mesulam, Marsel – Learning & Memory, 2004
A profound loss of cortical cholinergic innervation is a nearly invariant feature of advanced Alzheimer's disease (AD). The temporal course of this lesion and its relationship to other aspects of the disease have not yet been fully clarified. Despite assertions to the contrary, a review of the evidence suggests that a perturbation of cholinergic…
Descriptors: Alzheimers Disease, Symptoms (Individual Disorders), Neurology, Severity (of Disability)