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Pedreira, Maria Eugenia; Perez-Cuesta, Luis Maria; Maldonado, Hector – Learning & Memory, 2004
In previous experiments on contextual memory, we proposed that the unreinforced re-exposure to the learning context (conditioned stimulus, CS) acts as a switch guiding the memory course toward reconsolidation or extinction, depending on reminder duration. This proposal implies that the system computes the total exposure time to the context, from…
Descriptors: Stimuli, Memory, Context Effect, Experiments
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Maldonado, Hector; Romano, Arturo; Merlo, Emiliano; Freudenthal, Ramiro – Learning & Memory, 2005
Several studies support that stored memories undergo a new period of consolidation after retrieval. It is not known whether this process, termed reconsolidation, requires the same transcriptional mechanisms involved in consolidation. Increasing evidence supports the participation of the transcription factor NF-[Kappa]B in memory. This was…
Descriptors: Molecular Biology, Recall (Psychology), Long Term Memory, Animals