Two paradigms inform responses to active shooting situations: a traditional lockdown approach where individuals find cover in a classroom and lock the door, and a multi-option approach where individuals evacuate the area, create barricades, and, in last resort situations, actively resist the gunman. While a majority of schools conduct active shooter drills, typically using a traditional lockdown approach, little is known about their effectiveness. Through simulations, this study sought to determine which of the two paradigms that inform active shooter drills is the most effective. Drills informed by the multi-option response paradigm were found to end more quickly and result in fewer people being shot.