Despite governing agencies and universities pursuing evidence-based initiatives to promote positive health and well-being outcomes, intercollegiate student-athletes report significant barriers to mental wellness. According to cognitive affective stress model, coping strategies may reduce the likelihood of chronic stress and athlete burnout. As such, the purpose of this study was to examine the relationship between religious commitment, social support, and burnout among student-athletes at a religiously affiliated institution. Findings suggest both religious commitment and social support were significant predictors of athlete burnout. Interestingly though, religious commitment was positively associated with athlete burnout. Further investigation is required to examine the positive and negative nuances of religion on athlete burnout.