In 2002, the Swedish National Food Agency and researchers from Stockholm University made an announcement regarding the presence of acrylamide in carbohydrate-rich foods that are exposed to high temperatures, with cereals, potatoes, and coffee possibly being the most significant sources of ingestion. Although limited data are available on assessing…

The use of a multicompartment electrochemical cell for the potentiometric determination of solubility product constants of aqueous I[superscript -], Br[superscript -], SCN[superscript -], and Cl[superscript -] salts of silver is presented. An electrochemical cell presented in this study contained multiple half-cells made of disposable drinking…

The implementation of a laboratory exercise in an undergraduate chemistry course, where students perform a comparison of three different synthetic methods toward [Cu(Cl)(IPr)]-complexes (IPr = N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene), is described. The students are introduced to the continuous improvement of reactions in terms of green…

High-performance liquid chromatography (HPLC) experiments are an important part of the undergraduate analytical instrumentation laboratory courses and usually use commercial C18 silica-packed reversed-phase columns. In this experiment, a simple method of preparing SiO[subscript 2] core-shell packed columns was developed to enable students to…

Machine learning (ML) is extensively applied in chemistry, particularly in vibrational spectroscopy. However, few teaching examples effectively demonstrate the capabilities of ML in classifying polymeric materials, exhibiting subtle spectral differences that elude visual discrimination. This study presents a teaching example specifically tailored…

The urea cycle disorder drug glycerol phenylbutyrate (Ravicti) is presently one of the most expensive medications in the United States, with annual costs estimated at $800,000 as of 2023. An expedient synthesis of this orphan drug was successfully adapted for the undergraduate organic chemistry laboratory. Activation of 4-phenylbutyric acid with…

Liquid metals are widely applied in various fields, including chemistry, catalysis, energy storage, chemical sensing, and stretchable electronics, due to their unique deformabilities. However, their behavior under a rod or ring electrode has never been analyzed. Furthermore, research on the deformation behavior of eutectic Ga--In (EGaIn), the most…

Cyclopropane can be hydrogenated to produce propane under moderately high temperatures ([tilde]175 [degrees]C). Using a nanoparticle palladium catalyst, undergraduate students can explore the reaction and draw conclusions regarding the conditions for reaction. When deuterium is used, conclusions pertaining to the reaction mechanism are possible.…

Proteomics, or the study of the set of proteins in an organism, tissue, or cell, is a rapidly growing field within bioanalytical chemistry that can be used to investigate many biological questions. However, proteomics is not fully integrated into the undergraduate chemistry curriculum because of a lack of access to expertise, the cost of required…

Stereoselective reduction of ketones to alcohols using baker's yeast is a classic experiment in the undergraduate laboratory. Here we illustrate the reduction of racemic ethyl 2-fluoro-3-oxobutanoate to the corresponding alcohol using a set of four commercially available ketoreductases (KREDs). The reaction sets two stereocenters with four…

A renewed experimental procedure for the unknown carbonyl experiment has been developed using hydrazone synthesis, thin layer chromatography (TLC) analysis, and melting point determination to differentiate between structurally similar ketones and aldehydes in undergraduate organic chemistry practical courses. Benzaldehyde, p-tolualdehyde,…

Organic molecules are invisible objects, but they can be visualized and manipulated by using molecular models. The object-based learning (OBL) approach, which is an educational tool developed for museums and collection items, is tailored and applied to a first-year bachelor course of organic chemistry. At the beginning of the course, each student…

Metal-organic frameworks (MOFs) are porous materials composed of metal ions and organic ligands. These materials have garnered significant attention due to their wide-ranging applications, such as the capture of hazardous molecules, catalysis, production of value-added compounds, and detection of ions or molecules in water. Despite their immense…

The variation in the transference number of H[superscript +] (aq) is investigated for different HCl solution concentrations. The method for scribing graduations on electromigration tubes is modified to decrease the error in experimental measurements, and metallic copper is used as the anode to reduce the toxicity and environmental impact of the…

A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves…