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Teaching Undergraduate Physical Chemistry Lab with Kinetic Analysis of COVID-19 in the United States
Peer reviewed
Direct linkDylan K. Smith; Kristin Lauro; Dymond Kelly; Joel Fish; Emma Lintelman; David McEwen; Corrin Smith; Max Stecz; Tharushi D. Ambagaspitiya; Jixin Chen – Journal of Chemical Education, 2022
A physical chemistry lab for undergraduate students described in this report is about applying kinetic models to analyze the spread of COVID-19 in the United States and obtain the reproduction numbers. The susceptible-infectious-recovery (SIR) model and the SIR-vaccinated (SIRV) model are explained to the students and are used to analyze the…
Descriptors: Chemistry, Science Instruction, College Science, Undergraduate Students
Anna Laguta; Natalya Vodolazkaya; Dmitry Nerukh – Journal of Chemical Education, 2024
Chemistry experiments involving biological aspects are in high demand. This laboratory exercise blends biochemistry and physical chemistry, illustrates key concepts of the virus capsid surface, and is designed for a chemistry laboratory course for students majoring in biology in college. The experimental part provides a mastery of…
Descriptors: Undergraduate Students, Science Instruction, Chemistry, Biochemistry
Faville, Scott C.; Harris-Hamdscomb, Kes; Harker, Owain; Mattison, Stephanie; Tamorite, Hajie; Bristowe, Joshua; Daly, Daniel; Ege, Raissa; He, Haoyuan; Jones, Julian; McCorkindale, Abby; Mei, Kerry; Monson, Ashleigh; Moree, Lana; Perkovic, Finley; Rickerby, Georgia; Robinson, Jack; Rudkin, Felix; Whibley, Luke; Worthington, Rebecca; Ennis, Courtney; de la Harpe, Sara; Brind, Thomasin; Hopkins, Andrew; Winefield, Kaleb; Hendrickx, Sarah; Caljon, Guy; Perry, Benjamin; Vernall, Andrea J. – Journal of Chemical Education, 2022
An undergraduate laboratory was developed as part of the Drugs for Neglected Diseases "initiative's" Open Synthesis Network. This activity aimed to develop new compounds efficacious against visceral leishmaniasis. Students successfully synthesized, purified, and characterized ten different benzoxazole amides that were sent for biological…
Descriptors: College Science, Undergraduate Students, Laboratory Experiments, Diseases
Mohamed Touaibia; Natalie A. Levesque – Journal of Chemical Education, 2024
Heterocycles, more specifically those containing nitrogen, make up a family of molecules with great pharmaceutical potential. Many approved drugs, notably anticancer drugs, contain a nitrogen-based heterocycle. To expose students to this class of molecules, we used the Paal--Knorr reaction for the synthesis of edaravone, a pyrazolone derivative.…
Descriptors: Chemistry, College Science, Undergraduate Students, Undergraduate Study
Ronald Soong; Lindsey Fiddes; Jacob Pellizzari; Katelyn Downey; Monica Bastawrous; Antonio Adamo; Andre Simpson; Vivienne Luk – Journal of Chemical Education, 2023
Cryogenic electron microscopy (cryo-EM) is a powerful technique capable of characterizing large protein complexes that are otherwise impossible to characterize using traditional crystallography methods. Cryo-EM has played a pivotal role in our understanding of the structure--function relationship of the spike proteins on the COVID-19 viral…
Descriptors: Undergraduate Students, Chemistry, Science Instruction, Laboratory Experiments
Rachel C. Branco; Holly V. Goodson; Erin M. Jonasson – Journal of Chemical Education, 2022
Case studies are helpful teaching tools that can bring scientific concepts to life. Here, we present a case study related to protein-ligand interactions, amino acids, protein structure, and protein modification. While protein-ligand interaction is a foundational concept within Biochemistry, there are few available case studies that focus on this…
Descriptors: Biochemistry, Science Instruction, Chemistry, Alzheimers Disease
Download full textAlison J. Trew; Craig Early; Rebecca Ellis; Julia Nash; Katharine Pemberton; Paul Tyler; Timothy G. Harrison; Dudley E. Shallcross – Journal of Chemical Education, 2024
Topics associated with the chemical sciences form a significant part of the curriculum in science at the primary school level in the U.K. In this methodology paper, we demonstrate how a wide range of research articles associated with the chemical sciences can be disseminated to an elementary school audience and how children can carry out…
Descriptors: Chemistry, Scientific Research, Elementary School Students, Elementary School Teachers
King, David; Snyman, Magrieta; McGinitie, Elizabeth G. – Journal of Chemical Education, 2022
The global COVID-19 pandemic has had a significant impact on university course design, implementation, and instruction, with many courses being offered remotely rather than face-to-face to prevent the spread of COVID-19. As the COVID-19 pandemic subsides, more and more courses are transitioning back to face-to-face instruction. In this article, we…
Descriptors: Science Instruction, COVID-19, Pandemics, College Science
Elizabeth E. Karlsson; Jia-Hao Hu; Michael J. Davern; Yidan Cong; Jin Yan; Jason D. Surratt; Aleksandr V. Zhukhovitskiy – Journal of Chemical Education, 2022
The high demand for N95 and surgical masks made of nonbiodegradable petroleum-based materials due to SARS-CoV-2 challenges the recycling industry and is proving to be unsustainable. Although woven fabric masks present a longer lifetime, they are less effective in protecting against viral particulates. Here, through an at-home course-based…
Descriptors: Hygiene, Disease Control, Health Behavior, COVID-19
Fernández-Terán, Ricardo; Sucre-Rosales, Estefanía; Echevarría, Lorenzo; Hernández, Florencio E. – Journal of Chemical Education, 2020
Herein we present an engaging description of the existent analogy between social distancing during the COVID-19 pandemic and the collision cross-section of particles as defined in the collisional model for a chemical reaction. In addition, the link between collision cross-sections and kinetic rate constants is thoroughly established, bridging…
Descriptors: COVID-19, Pandemics, Disease Control, Scientific Concepts
Sucre-Rosales, Estefanía; Fernández-Terán, Ricardo; Carvajal, David; Echevarría, Lorenzo; Hernández, Florencio E. – Journal of Chemical Education, 2020
Herein, we present an experience-based learning approach that uses the COVID-19 pandemics knowledge about virus spread and epidemics to establish an analogy between a simple epidemics model--the SIR model (susceptible--infected--removed), and a second-order autocatalytic reaction with subsequent catalyst deactivation. Our approach provides a…
Descriptors: COVID-19, Pandemics, Communicable Diseases, Microbiology
Barnett, Kerry L.; Shea, Kevin M.; McGeough, Catherine; Trotta, Kristine; Williams, Steven; Ly, Minh; Aloisio, Kathryn – Journal of Chemical Education, 2020
A semester-long research project for second-semester organic chemistry lab sections was developed. Student projects were based on preliminary data from faculty research that suggested the natural product neurolenin B to be a treatment for lymphatic filariasis. Students isolated neurolenins from the Central American plant "Neurolaena…
Descriptors: Organic Chemistry, Science Instruction, Scientific Concepts, Science Laboratories
Armstrong, David; Poë, Judith C. – Journal of Chemical Education, 2020
The Science of Human Health is an undergraduate chemistry course for non-science majors. This course presents chemistry content following a systems thinking approach and was created with the goal of providing students with the necessary chemistry foundation to make informed decisions which will affect their own well-being and their global…
Descriptors: Chemistry, College Science, Nonmajors, Undergraduate Students
Andrews, Jessica L.; de Los Rios, Juan Pablo; Rayaluru, Mythreyi; Lee, Seungwon; Mai, Lilly; Schusser, Anna; Mak, Chi H. – Journal of Chemical Education, 2020
During the COVID-19 pandemic, an at-home laboratory program was created and implemented for a section of the general chemistry course at the University of Southern California. The experiments were designed to only utilize safe household items and no special equipment. These laboratory activities, spanning over 4 weeks, focused on concepts usually…
Descriptors: Science Instruction, Chemistry, Disease Control, School Closing
Aguilar, Noberto; Garcia, Billy; Cunningham, Mark; David, Samuel – Journal of Chemical Education, 2016
A synthesis of the "R,R"-tartrate salt of the popular anti-Parkinson's drug "R"-rasagiline (Azilect) was adapted to introduce the organic laboratory student to a medically relevant synthesis. It makes use of concepts found in the undergraduate organic chemistry curriculum, appropriately fits into three approximately 4 h lab…
Descriptors: Diseases, Neurological Impairments, Drug Therapy, Organic Chemistry
