Cycloadditions in combination with multicomponent reactions are among the most valuable synthetic tools used by organic chemists to construct cyclic and heterocyclic compounds in a straightforward way. Although cycloadditions, such as the Diels--Alder reaction, are mainly covered in basic and advanced organic courses for undergraduate students,…

Silver and its compounds have been widely used in experimental teaching, industrial production, and other fields. In these processes, a large amount of wastewater containing silver is usually produced, which might contribute to environmental pollution. Therefore, recycling silver from wastewater not only has good economic value but also meets the…

One of the greatest challenges in a student's ability to successfully complete reactions in organic chemistry is the ability to differentiate between reactions that have similar structures and proceed through similar reaction mechanisms. Featured in this article is an interleaved reaction review activity called a reaction web. Students are divided…

Nanozyme is a kind of mimetic enzyme possessing unique properties of nanomaterials and catalytic functions of natural enzymes. The nanozymes have the characteristics of high catalytic efficiency and good stability and are widely utilized in medicine, chemical industry, food, agriculture, and environment. This laboratory experiment is designed for…

Previous educational articles on microfluidic technology mainly focused on continuous microfluidics, so we set up an undergraduate laboratory experiment to introduce droplet microfluidics to students. Students can understand the concept of microfluidic channels and the principles of droplet microfluidics, prepare polydimethylsiloxane (PDMS)…

The addition of a small excess of triethyl orthoformate to an alcoholic mixture of NiCl[subscript 2]·6H[subscript 2]O and triphenylphosphine (PPh[subscript 3]) results in an increase in the typical isolated yield of [NiCl[subscript 2](PPh[subscript 3])[subscript 2]] from below 50% to over 85%. The impact of water when present in the reaction…

This article describes a program that was developed to introduce senior high school students in Melbourne, Australia to the technique of X-ray crystallography within the context of chemistry research. Students had an opportunity for original experimentation, performing reactions and attempting to grow crystals of reaction products in a school…

Teaching green chemistry within the K-12 classroom has a positive impact on attitudes and perceptions of chemistry in society for future scientists and professionals, resulting in safer, less hazardous chemistry experiments and demonstrations. The state of New York has taken advantage of the benefits that green chemistry provide in the classroom…

The essential component of expanding an undergraduate curriculum is the inclusion of lab experiments in nanoscience and nanomaterials, which significantly impact health and the environment through their use in food, cosmetics, agriculture, and medicine. We designed a laboratory experiment based on the atomic force microscopy (AFM) analysis of the…

The American Chemical Society advocates a shift from rule-based to risk-based safety education for chemistry graduates, emphasizing meaningful student engagement in the risk assessment process for laboratory work. To implement this paradigm shift, we introduced RAMP (Recognize Hazards, Assess Risk, Minimize Risk, and Prevent Emergencies)-based…

Molecular imprinting technology holds significant potential for applications in chemical analysis and detection. In order to integrate the fundamental knowledge of polymer chemistry, electrochemistry, and analytical chemistry with practical applications and cutting-edge research, we proposed a comprehensive experiment of the preparation,…

Metabolism is always a challenging topic in biochemistry. In our project, a courseware called "Metabolism Metro" was developed. "Metabolism Metro" is a self-learning tool which aims to facilitate students learning of metabolic pathways in an interactive and easy-to-understand manner. The courseware includes both pre-class and…

A major challenge when designing new experiments for the general chemistry laboratory is introducing students to the necessary techniques while keeping the experiment engaging and accessible. This work presents a new multiweek activity designed to introduce students to advanced instrumentation in the form of high-performance liquid chromatography…

Chirality continues to intrigue scientists because of its implications in various scientific areas, including the long-unsolved question of its development and link with the origin of life. Chirality plays a significant role in medicine with the advent of chiral drugs and the consequent importance of asymmetric synthesis. For many undergraduate…

An integrated laboratory experience in X-ray photoelectron spectroscopy (XPS) is designed for undergraduate and graduate students in chemistry, materials science, and other related fields. Focusing on ubiquitous Si, Cu, and their common oxides, students are guided to characterize a series of standard materials by XPS to understand the fundamentals…