Blue (B), yellow (Y), red (R), and green (G) color-changing dye was used in a general chemistry course for first-year undergraduate students with nonscience majors to highlight the redox reactions written as the gain and loss of hydrogen. The first experiment is a vibrant color variation using a synthetic dye of indigo carmine. The second…

An upper-division undergraduate- or graduate-level laboratory experiment, challenging students to identify bovine serum albumin, equine myoglobin, bovine calmodulin, and bovine cytochrome c, uses four methods of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS): linear positive, in-source decay, peptide…

The Leidenfrost nanochemistry synthesis of gold colloids was introduced in this "Journal" as an advanced method to synthesize gold nanoparticles during an undergraduate nanochemistry research project. When trying to repeat these experiments in the laboratory, we experienced difficulties in the synthesis of the gold nanoparticles since…

BYOL (Bring Your Own Lime), a novel laboratory experiment, is introduced in this paper. Students are encouraged to bring affordable household and grocery store chemicals into the classroom. The Bring Your Own Chemical (BYOC) concept demonstrates to students that food and household products are chemicals too. Citruses are often used to highlight…

The dehydration of 2- or 4-methylcyclohexanol to obtain isomers of methylcyclohexene is a classic organic chemistry experiment. Students perform a distillation, collecting samples to analyze the progress of the reaction. The reaction produces a major product that can be explained on the basis of the regiochemistry of the [pi] bond formation for…

We report on a simple, rapid, and room-temperature undergraduate-level experiment for gold nanoparticle synthesis, analysis, and utilization as a catalyst for the sodium-borohydride-assisted reduction of methylene blue and Congo red dyes. Typical procedures toward gold nanoparticle formation require an elaborate, lengthy synthesis (some requiring…

The concept of equilibrium vapor pressure plays a key role in the general chemistry curriculum; it is among the first and most easily demonstrated examples of equilibrium and frequently caps off the first semester of general chemistry where it illustrates the properties of liquids and intermolecular forces. We report here simple modifications of…

All-solid-state polymer electrolytes (SPEs) have been regarded as an advisible alternative for simultaneously overcoming the safety issues and high energy density demands presented in traditional lithium batteries, and they represent the development orientation of energy storage devices. This course describes the preparation of a cross-linked and…

Secondary metabolite compounds contained in each plant genus have certain characteristics, which is true also of the flavonoid in the genus "Artocarpus." In the experiment described here, third-year undergraduate students performed the isolation and characterization of cycloartocarpin from the roots of "Artocarpus altilis"…

According to the definition, surface tension could be affected not only by intermolecular interaction but also by molecular area. However, in chemistry textbooks, surface tension is mainly explained only in terms of intermolecular interaction. Although the existing surface tension concept in the textbooks can lead to a variety of counterexamples,…

A laboratory exercise for the synthesis of a sulfonated styrene-"co"-maleic anhydride polymer and its application as a stain blocker on nylon-6,10, is described. The effectiveness of the sulfonated polymer to prevent the conjugate base of an acid dye from staining the polyamide is demonstrated. This experiment is designed for…

Although teaching laboratories offer students the opportunity to act and think like chemists, in many cases students simply follow written procedures to generate predetermined outcomes. In recent years, there has been a movement toward inquiry-, problem-, and discovery-based learning. In a similar vein, the first-semester introductory organic…

"N"-Formamides are important intermediates in the synthesis of many pharmacologically active compounds and are used as protecting groups for amines or as catalysts in different reactions. The current "N"-formylation experiment is designed as a part of an introductory organic chemistry course for undergraduate students. The…

Water electrolysis, a well-known and simple experiment, confirms that a water molecule comprises hydrogen and oxygen atoms. In this experiment, hydroxide or hydrogen ions generated from each electrode were identified using an indicator based on the assumption that electrodes, electrolytes, and indicators do not participate in the water…

We have expanded Stein's "Sweetness of Aspartame" laboratory project (Stein, P. J. "J. Chem. Educ." 1997, 74, 1112, DOI: 10.1021/ed074p1112) to include extensive use of statistical testing. Students test the statistical significance of a nonzero intercept in a linear regression, bias in comparison to a true value, and…