This laboratory experiment introduces upper-division undergraduate analytical chemistry students to liquid chromatography-tandem mass spectrometry (LC-MS/MS) in a forensic application: the analysis of cocaine and metabolites of cocaine in simulated serum ostensibly from drug overdose victims. For this investigation, students developed the…

This three-part laboratory experiment investigates key aspects of the Buchwald-Hartwig amination cross-coupling reaction through guided-inquiry learning strategies. The first part of this experiment utilizes high-throughput experimentation techniques to reinforce, explore, and extend fundamental concepts that are represented in the classroom,…

A traditional laboratory course with the primary learning outcome of improving students' theoretical knowledge has received much criticism over the years due to the lack of evidence that these goals have achieved. We report our efforts to redesign a traditional first-year organic and inorganic (also known as synthetic) laboratory course from…

The Making Introductory Courses Real while Online (MICRO) laboratory project was developed to meet the need for hands-on experiments, focused on topics in analytical chemistry, to be delivered safely remotely or in a socially distanced in-person lab. Unlike more traditional lab experiments, MICRO laboratories use only microgram or nanogram amounts…

Infrared (IR) spectroscopy is a vibrational spectroscopic technique useful in chemical, pharmaceutical, and forensic sciences. It is essential to identify chemicals for reasons spanning from scientific research and academic practices to quality control in companies. However, in some university degrees, graduate students do not get the proficiency…

In this laboratory experiment, students explore the aquatic photochemical fate of ranitidine and cimetidine, two common pharmaceutical pollutants found in wastewater. It provides an engaging environmental context for students to develop knowledge of reaction kinetics and photochemistry as well as skill in using analytical instrumentation. This…

A remote laboratory that measures the enthalpy of vaporization ([delta]"H"[subscript vap]°) and the entropy of vaporization ([delta]"S"[subscript vap]°) of "n"-octane was designed, constructed, and offered to second-year physical chemistry undergraduates at the University of New England (UNE) and Curtin University.…

An organic chemistry experiment designed for senior undergraduates focuses on bifunctional catalysis, a critical yet often omitted topic at the undergraduate level, but essential for advanced studies in chemistry. By utilization of a tertiary amine-thiourea catalyst in the asymmetric Michael addition reaction, the experiment showcases the…

Artificial intelligence (AI) and data science (DS) are receiving a lot of attention in various fields. In the educational field, the need for education utilizing AI and DS is also being emerged. In this context, we have created an AI/DS integrating program that generates a compound classification/regression model using characteristics of compounds…

Conventional mobile phone colorimetry usually utilizes the RGB color mode to measure concentration of solutions, but the paper entitled "Determining the Amount of Copper(II) Ions in a Solution Using a Smartphone" proposes the use of hue ("H") to measure the concentration. It is pointed out that the "H" value increases…

Hands-on experiences in analytical chemistry laboratories are essential to improve students' technical skills on handling analytical glassware and instruments, but the coronavirus pandemic in 2020-2021 disrupted such learning activities. Thus, alternative remote activities are required to supplement practical skills. In this work, a new portable…

In this guided inquiry experiment, students extract catecholase enzyme from apples to catalyze the oxidation of catechol. They follow the reaction using the UV--vis absorbance of the "p"-benzophenone produced to determine the Michaelis-Menten kinetic parameters. Students make selected experimental choices within a structured framework…

Raman spectroscopy is an important vibrational spectroscopy tool to characterize chemical compounds. As only a few photons undergo Raman scattering, enhancement of signal is a vital requirement. In this laboratory experiment, some practical aspects of Raman spectroscopy and how a simple enhancement procedure can be used to detect a Raman signal…

The spectrophotometric determination of the percent composition of an aspirin tablet is a common first-year, general chemistry undergraduate laboratory procedure. The experiment requires that a known amount of pure acetylsalicylic acid be quantitatively converted into the soluble disodium salicylic acid that is further reacted with excess…

A symmetry activity using student-built models was developed in line with faculty-developed pedagogical goals and a collaborative learning framework. The activity took place in a 3-h laboratory portion of an upper-division inorganic chemistry course. It required students to identify symmetry elements for seven molecules using common 2D…