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Drug Discovery in Real Life: An Online Learning Activity for Bioinformatics Students
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Jessica K. Holien; Lachlan Coff; Andrew J. Guy; Jennifer C. Boer – Journal of Chemical Education, 2023
During COVID-19 lockdowns, online learning activities had to be developed for the Undergraduate and Masters by Coursework Bioinformatics students at RMIT University. Therefore, we designed an integrative, industry-based research assignment, which guided the students through a drug discovery project from target identification to lead optimization.…
Descriptors: Chemistry, Drug Therapy, Science Instruction, Undergraduate Students
A Multidisciplinary Team-Based Classroom Exercise for Small Molecule Drug Discovery
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Charlotte A. Dodson; Stephen E. Flower; Mark Thomas – Journal of Chemical Education, 2023
Industrial drug discovery teams encompass scientists from multiple specialties and require participants to communicate effectively across disciplinary boundaries. In this paper, we present an undergraduate or graduate classroom simulation of this environment. Over a series of five workshops, student teams of mixed scientific backgrounds perform…
Descriptors: Drug Therapy, Pharmacy, Teamwork, Interdisciplinary Approach
Increasing Computational Protein Design Literacy through Cohort-Based Learning for Undergraduate Students
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Erin C. Yang; Robby Divine; Christine S. Kang; Sidney Chan; Elijah Arenas; Zoe Subol; Peter Tinker; Hayden Manninen; Alicia Feichtenbiner; Talal Mustafa; Julia Hallowell; Isiac Orr; Hugh Haddox; Brian Koepnick; Jacob O'Connor; Ian C. Haydon; Karla-Luise Herpoldt; Kandise Van Wormer; Celine Abell; David Baker; Alena Khmelinskaia; Neil P. King – Journal of Chemical Education, 2022
Undergraduate research experiences can improve student success in graduate education and STEM careers. During the COVID-19 pandemic, undergraduate researchers at our institution and many others lost their work-study research positions due to interruption of in-person research activities. This imposed a financial burden on the students and…
Descriptors: Undergraduate Students, Teaching Methods, COVID-19, Pandemics
Bridging the Gap between Instructional and Research Laboratories: Teaching Data Analysis Software Skills through the Manipulation of Original Research Data
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Hansen, Sarah J. R.; Zhu, Jieling; Karch, Jessica M.; Sorrento, Cristina M.; Ulichny, Joseph C.; Kaufman, Laura J. – Journal of Chemical Education, 2016
The gap between graduate research and introductory undergraduate teaching laboratories is often wide, but the development of teaching activities rooted within the research environment offers an opportunity for undergraduate students to have first-hand experience with research currently being conducted and for graduate students to develop…
Descriptors: Science Instruction, Science Laboratories, Scientific Research, Data Analysis
Understanding Least Squares through Monte Carlo Calculations
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Tellinghuisen, Joel – Journal of Chemical Education, 2005
The method of least squares (LS) is considered as an important data analysis tool available to physical scientists. The mathematics of linear least squares(LLS) is summarized in a very compact matrix rotation that renders it practically "formulaic".
Descriptors: Data Analysis, Least Squares Statistics, Monte Carlo Methods, Scientific Research
Fitting of a Straight Line when Both Variables Contain Errors. Application to the Beer-Lambert Law.
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Tan, H. S.; Jones, W. E. – Journal of Chemical Education, 1989
Offers an improvement over the least-square method that is particularly applicable to fitting the Beer-Lambert equation. Provides typical data and the corresponding graphs. Lists six references. (YP)
Descriptors: Chemistry, College Science, Data Analysis, Higher Education
Doing Science and Asking Questions: An Interactive Exercise.
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Middlecamp, Catherine Hurt; Nickel, Anne-Marie L. – Journal of Chemical Education, 2000
Describes an exercise designed to allow for student introductions at the beginning of a new semester while simultaneously revealing ways in which research questions can be constructed to collect data. (WRM)
Descriptors: Data Analysis, Data Collection, Higher Education, Questioning Techniques