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Costin, Gertrude-Emilia; Miller, Adele – Journal of Biological Education, 2022
The advancement of breakthrough concepts in science and their implementation in society can only be achieved by starting early with the education of new generations of scientists. The concept of 'Replacement, Reduction and Refinement' (the 3Rs) in regards to animal use was first described by Russell and Burch in 1959. The 3Rs have nowadays a…
Descriptors: Science Instruction, Toxicology, Animals, Elementary Secondary Education