We used social relations modeling (SRM; mixed modeling and SOREMO) to examine liking among peers ("affective preferences") in relation to gender and socioemotional problems. Participants (N = 278, age 10 to 13) rated how much they liked each other and reported depressive symptoms, negative beliefs, and social worries. Boys and girls were equally liked, but liked same-gender more than cross-gender peers. Genders showed similar consensus about liking for same-gender peers; rater differences were important for cross-gender liking. Depressed preadolescents were liked less but did not like classmates less. Participants who attributed more negative qualities to peers were less liked "and" liked others less. SRM showed no associations between worry and affective preferences, whereas others analyses indicated those with high worry were less liked. SRM results were compared to results using more typical methods, and recommendations were made for using same-gender vs. cross-gender ratings and summary affective preference scores. (Contains 4 tables.)