Extant research indicates that inmates with street gang history are prone for prison misconduct but that inmates convicted of homicide offenses are less likely to be noncompliant. No research has explored the interaction between street gang history and homicide offending. Based on official infraction data from 1,005 inmates selected from the Southwestern United States, the current study found that inmates with street gang history and convictions for homicide offenses were significantly involved in six types of institutional misconduct, net the effects of homicide offending, offense severity, street and prison gang risk, violence history, and demographics. Implications for theory and research are explored. (Contains 6 tables and 7 notes.)