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Direct linkvan Tricht, M. J.; Nieman, D. H.; Bour, L. J.; Boeree, T.; Koelman, J. H. T. M.; de Haan, L.; Linszen, D. H. – Brain and Cognition, 2010
Abnormalities in eye tracking are consistently observed in schizophrenia patients and their relatives and have been proposed as an endophenotype of the disease. The aim of this study was to investigate the performance of patients at Ultra High Risk (UHR) for developing psychosis on a task of smooth pursuit eye movement (SPEM). Forty-six UHR…
Descriptors: Eye Movements, Schizophrenia, Patients, Human Body
O'Driscoll, Gillian A.; Callahan, Brandy L. – Brain and Cognition, 2008
Abnormal smooth pursuit eye-tracking is one of the most replicated deficits in the psychophysiological literature in schizophrenia [Levy, D. L., Holzman, P. S., Matthysse, S., & Mendell, N. R. (1993). "Eye tracking dysfunction and schizophrenia: A critical perspective." "Schizophrenia Bulletin, 19", 461-505]. We used meta-analytic procedures to…
Descriptors: Maintenance, Schizophrenia, Patients, Effect Size
Calkins, Monica E.; Iacono, William G.; Ones, Deniz S. – Brain and Cognition, 2008
Several forms of eye movement dysfunction (EMD) are regarded as promising candidate endophenotypes of schizophrenia. Discrepancies in individual study results have led to inconsistent conclusions regarding particular aspects of EMD in relatives of schizophrenia patients. To quantitatively evaluate and compare the candidacy of smooth pursuit,…
Descriptors: Eye Movements, Schizophrenia, Patients, Genetics
Reilly, James L.; Lencer, Rebekka; Bishop, Jeffrey R.; Keedy, Sarah; Sweeney, John A. – Brain and Cognition, 2008
The increasing use of eye movement paradigms to assess the functional integrity of brain systems involved in sensorimotor and cognitive processing in clinical disorders requires greater attention to effects of pharmacological treatments on these systems. This is needed to better differentiate disease and medication effects in clinical samples, to…
Descriptors: Narcotics, Eye Movements, Schizophrenia, Diseases
Rommelse, Nanda N. J.; Van der Stigchel, Stefan; Sergeant, Joseph A. – Brain and Cognition, 2008
The neural substrates of eye movement measures are largely known. Therefore, measurement of eye movements in psychiatric disorders may provide insight into the underlying neuropathology of these disorders. Visually guided saccades, antisaccades, memory guided saccades, and smooth pursuit eye movements will be reviewed in various childhood…
Descriptors: Eye Movements, Schizophrenia, Pervasive Developmental Disorders, Children
