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Nelson, Linda D.; Scheibel, Kevin E.; Ringman, John M.; Sayre, James W. – Brain and Cognition, 2007
Measures developed from animal models of aging may detect dementia of the Alzheimer's type in a population at-risk for Alzheimer's disease (AD). Although, by middle age, individuals with Down syndrome (DS) show an extraordinarily high prevalence of AD-type pathology, their severe idiopathic cognitive deficits tend to confound the "clinical"…
Descriptors: Pathology, Animals, Alzheimers Disease, Down Syndrome