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Direct linkJurkowski, A.J.; Stepp, E.; Hackley, S.A. – Brain and Cognition, 2005
The effect of a visual warning signal (1.0-6.5s random foreperiod, FP) on the latency of voluntary (hand-grip) and reflexive (startle-eyeblink) reactions was investigated in Parkinson's disease (PD) patients and in young and aged control subjects. Equivalent FP effects on blink were observed across groups. By contrast, FP effects diverged for…
Descriptors: Patients, Diseases, Animals
Peer reviewedNelson, Linda D.; Scheibel, Kevin E.; Ringman, John M.; Sayre, James W. – Brain and Cognition, 2007
Measures developed from animal models of aging may detect dementia of the Alzheimer's type in a population at-risk for Alzheimer's disease (AD). Although, by middle age, individuals with Down syndrome (DS) show an extraordinarily high prevalence of AD-type pathology, their severe idiopathic cognitive deficits tend to confound the "clinical"…
Descriptors: Pathology, Animals, Alzheimers Disease, Down Syndrome
