Fox and his colleagues (May-June 2009) listed three occurrences beginning in the 1980s that have dampened psychologists' desires to procure the right to prescribe psychotropic medications. That research review highlighted the fact that antidepressants produce a very modest effect at best when compared with placebos. I briefly summarize here some…

Greenberg (2010) is correct in his assertion that the investigational heuristic used to measure the efficacy of antidepressants is flawed. Robust placebo effects are endemic in the psychiatric literature, particularly in studies of antidepressants, and estimates of placebo responding have increased over time (Rief et al., 2009). In the case of…