This article provides both an experiment and a framework for discussion that students can use to compare the efficiency of producing ethanol by using corn versus sugarcane as a raw material.

Students need practice in proposing hypotheses, developing experiments that will test these hypotheses, and generating data that they will analyze to support or refute them. I describe a guided-inquiry activity based on the "tongue map" concept, appropriate for middle school and high school students.

Undergraduate biology education is undergoing dramatic changes, emphasizing student training in the "tools and practices" of science, particularly quantitative and problem-solving skills. We redesigned a freshman ecology lab to emphasize the importance of scientific inquiry and quantitative reasoning in biology. This multi-week investigation uses…

Although the development of next-generation (NextGen) sequencing technologies has revolutionized genomic research and medicine, the incorporation of these topics into the classroom is challenging, given an implied high degree of technical complexity. We developed an easy-to-implement, interactive classroom activity investigating the similarities…

In daily life, students are allowed to use words such as "more," "some," or "increase-decrease" to describe the relationship between two events. In science, concise description is necessary, which requires the contribution of math. In the summer component of the Science Research Institute program, students integrated…

As advances in biotechnology and molecular biology rapidly expand in research settings, it is vital that we continue to prepare high school students to enter and thrive in those modern laboratories. This multistep, inquiry-based lab describes highly adaptable methods to teach students not only current molecular techniques and technologies, but…

We developed an interactive laboratory that allows students to identify and grade tissue samples from human breast biopsies, using techniques similar to those used by actual pathologists. This unique lab develops a practical and intellectual understanding of basic tissue structures that make up living systems, utilizing technology to bring…

Introducing students to the process of scientific inquiry is a major goal of high school and college labs. Environmental toxins are of great concern and public interest. Modifications of a vertebrate developmental toxicity assay using the frog Xenopus laevis can support student-initiated toxicology experiments that are relevant to humans. Teams of…

The polymerase chain reaction (PCR) is a common technique used in high school and undergraduate science teaching. Students often do not fully comprehend the underlying principles of the technique and how optimization of the protocol affects the outcome and analysis. In this molecular biology laboratory, students learn the steps of PCR with an…

Implementation of a guided-inquiry lab in introductory biology classes, along with scaffolded instruction, improved students' understanding of the scientific method, their ability to design an experiment, and their identification of experimental variables. Pre- and postassessments from experimental versus control sections over three semesters…

It is certainly widely appreciated that there is much to be gained in the fertile crosstalk between science and history--whether bringing a historical perspective into the science classroom (Wieder, 2006) or a scientific perspective to the study of history (McElvaine, 2002; Smail, 2008). Perhaps the major impetus for using history in teaching…

Using an interactive map-based PDF, students learn key concepts related to biodiversity while developing data-analysis and critical-thinking skills. The Bird Island lesson provides students with experience in translating geospatial data into bar graphs, then interpreting these graphs to compare biodiversity across ecoregions on a fictional island.…

Natural selection and other components of evolutionary theory are known to be particularly challenging concepts for students to understand. To help illustrate these concepts, we developed a simulation model of microevolutionary processes. The model features all the components of Hardy-Weinberg theory, with population size, selection, gene flow,…

The predator-prey relationship is one of the most recognizable and well-studied animal relationships. One of the more striking aspects of this relationship is the differential natural selection pressure placed on predators and their prey. This differential pressure results from differing costs of failure, the so-called life-dinner principle. If a…

Light pollution negatively affects many nocturnal organisms. We outline two experiments that can be conducted by students to examine the effects of light pollution on firefly behavior. Inexpensive electronic light sensors, which are easy to construct and calibrate, are used to sample light levels along transects in spaces where fireflies are…