Nanoscale science and engineering are disciplines that examine the unique behaviors and properties of materials that emerge at the size range of 1 to 100 nanometers (a billionth of a meter). Nanobiotechnology is a sub-discipline of nanoscience that has arisen more recently. Nanobiotechnology is already impacting the fields of healthcare and biomedical engineering, and promises to be critical in advances in other related fields. Even though it spans multiple science disciplines, the abstract nature of nanoscience in general can challenge instructors to find practical ways to teach about this concept in the classroom. This article describes a quick and simple laboratory investigation for high school or undergraduate students utilizing nanotechnology in a biological context. It addresses biology content standards in both personal and community health as well as the future challenges of science and technology to society. This activity requires a limited amount of materials and yields visible results. The investigation has two basic objectives: (1) make students aware of nanotechnology and its potential biological interface; and (2) have students examine and explore the accuracy of claims made about emerging technologies. (Contains 3 figures and 1 table.)