This article introduces and contextualizes the content of this theme issue of "The American Biology Teacher" (ABT), which focuses on integrating elements of the history of science (HOS) in biology instruction. Such orientations can enhance students' understanding of core biological concepts and the process of scientific discovery by…

Evolutionary medicine is a growing area of research and practice; however, it is not widely discussed in introductory biology courses. Because of the interest in human biology, using evolutionary medicine is a great way to hold students' interest, placing topics in context, making the subject of evolution relevant. Too often students lose interest…

The discovery of and research into penicillin resistance by Sir Edward Abraham and Sir Ernst Chain can be used to teach the concept of natural selection and also multiple nature of science (NOS) objectives associated with Next Generation Science Standards, such as "scientific knowledge is based on empirical evidence" and "science is…

We present results from the first year of a three-year extramurally funded project involving a partnership between an ethnically diverse urban high school and professional research botanists. The goals are to provide students exposure to real-world science, broaden interest in scientific fields of study, and increase floristic data and herbarium…

Case studies are valuable tools for instruction but are often limited to a single topic and a single class period. Courses such as evolution that synthesize multiple concepts around a common theme, however, can use a single case study type project that extends over the entire semester to develop and link core concepts. A central theme in…

Hands-on learning is a highly effective teaching method for topics in STEM disciplines. Unfortunately, environmental science teachers sometimes lack the tools to engage their students in hands-on experimentation in real-world research outside of the classroom. Partnerships between science professionals and teachers can help address this disparity,…

Recent scientific studies are providing increasing evidence for how microbes living in and on us are essential to our good health. However, many students still think of microbes only as germs that harm us. The classroom activities presented here are designed to shift student thinking on this topic. In these guided inquiry activities, students…

Does working with first- and second-hand ecological data improve students' knowledge of ecological ideas, motivation and engagement in science, data exploration, and citizenship skills (students' ability to make informed decisions)? We have been exploring this question with high school science teachers in New York State for the past year using a…

This article explains four kinds of inquiry exercises, different in purpose, for teaching advanced-level high school and college students the hypothetico-deductive (H-D) method. The first uses a picture of a river system to convey the H-D method's logic. The second has teams of students use the H-D method: their teacher poses a hypothesis…

We present a class discussion that took place in the second author's high school biology class. Working from video data that we transcribed, studied, and analyzed closely, we recount how the question "Is air matter?" posed at the beginning of a unit on photosynthesis led to student-driven inquiry and learning. This case study illustrates what we…

New science standards and reform recommendations spanning grades K--16 focus on a limited set of key scientific concepts from each discipline that all students should know. They also emphasize the integration of these concepts with science practices so that students learn not only the "what" of science but also the "how" and…

We propose a procedure for the assay of fermentation in yeast in microcentrifuge tubes that is simple and rapid, permitting assay replicates, descriptive statistics, and the preparation of line graphs that indicate reproducibility. Using regression and simple derivatives to determine initial velocities, we suggest methods to compare the effects of…

Using Pompe disease as a context affords the opportunity for students to consider multiple biological concepts and embraces the Next Generation Science Standards Disciplinary Core Ideas Structure and Function (LS1.A) and Inheritance of Traits (LS3.A) as well as Crosscutting Concepts Structure and Function and Cause and Effect. These crosscutting…

I describe a quantitative approach to three case studies in evolution that can be used to challenge college freshmen to explore the power of natural selection and ask questions that foster a deeper understanding of its operation and relevance. Hemochromatosis, the peppered moth, and hominid cranial capacity are investigated with a common algebraic…

Natural selection is the mechanism of evolution caused by the environmental selection of organisms most fit to reproduce, sometimes explained as "survival of the fittest." An example of evolution by natural selection is the development of bacteria that are resistant to antimicrobial agents as a result of exposure to these agents. Triclosan, which…