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ERIC Number: EJ1287751
Record Type: Journal
Publication Date: 2021-Mar
Pages: 4
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-1043-4046
EISSN: N/A
Available Date: N/A
A Classic Experiment Revisited: Membrane Permeability Changes during the Action Potential
Powell, Carolyn L.; Brown, Angus M.
Advances in Physiology Education, v45 n1 p178-181 Mar 2021
The ability to understand the relationship between the reversal potential and the membrane potential is a fundamental skill that must be mastered by students studying membrane excitability. To clarify this relationship, we have reframed a classic experiment carried out by Hodgkin and Katz, where we compare graphically the membrane potential at three phases of the action potential (resting potential, action potential peak, and afterhyperpolarization) to reversal potential for K[superscript +] (E[subscript K]), reversal potential for Na (E[subscript Na]), and membrane potential (E[subscript m]) (calculated by the Goldman Hodgkin Katz equation) to illustrate that the membrane potential approaches the reversal potential of the ion to which it is most permeable at that instant.
American Physiological Society. 9650 Rockville Pike, Bethesda, MD 20814-3991. Tel: 301-634-7164; Fax: 301-634-7241; e-mail: webmaster@the-aps.org; Web site: https://bibliotheek.ehb.be:2487/journal/advances
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A
Author Affiliations: N/A