Discusses the difficulties involved in determining the cost of clinical research in light of the changing health care market. These include confusion about terminology, lack of specificity, estimation of the cost of complications, duration of patient participation, and the assignment of personnel and infrastructure costs. (MDM)

Presents the findings of the Association of American Medical Colleges' Working Group on Preserving Medical Schools' Academic Mission in a Competitive Marketplace. Concludes that medical schools will take a variety of approaches to define and preserve their missions and that the importance of the core mission of education and research is likely to…