Mental health concerns among K-12 students are prevalent, including students who present with complex conditions such as Obsessive-compulsive disorder (OCD) (Moon et al., 2017). The Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) explains that "characteristic symptoms of OCD are the presence of obsessions and/or compulsions" (American Psychological Association [APA], 2022, p. 263). The DSM defines obsessions as "repetitive and persistent thoughts, images, or urges. Compulsions (or rituals) are repetitive behaviors or mental acts" (APA, 2022, p.267). To examine school mental health, this study uses a multi-disciplinary lens including both education and mental health to investigate teachers' understanding of OCD, their perceived abilities to teach and support students with OCD, and factors that impact their potential abilities. Using a quantitative approach to provide interpretations of teachers' perceptions, results highlight implications for both in-service and pre-service development related to mental illness and potential collaboration between general and special education teachers, school counselors, and school psychologists.