This practical guide has been developed to help facilitate collaboration and build effective partnerships at the local level between local educational agency (LEA) and vocational rehabilitation (VR) personnel. Unfortunately, there is no magic formula that will instantly create these partnerships; however, there are proven strategies and processes that when established, will help facilitate building effective collaborative partnerships. This guide is divided into four sections with a variety of resources provided in the appendix. The four sections are: (1) A Shared Understanding of Transition Services which provides an overview of Workforce Innovation and Opportunity Act (WIOA) amendments to the Rehabilitation Act and Individuals with Disabilities Education Act (IDEA), offering a foundation to begin or enhance collaboration between VR and LEAs and schools; (2) Building Local Partnerships where day-to-day and annual practices are outlined that can be incorporated into local level collaboration to improve effectiveness of the partnership; (3) Coordination and Collaboration for Individualized Student Planning which outlines ways partners can identify roles and responsibilities to support the students as they guide their transition planning towards desired post-school goals; and (4) Partnering with Families: Reimagining the Possibilities is devoted to the importance of family involvement and provides practical strategies on new ways to collaborate with families. The Guide sections are designed to provide the processes and steps necessary to build effective collaboration at the local level; specifically between educators, VR counselors, parents, and other staff involved in assisting students with disabilities in preparing for, obtaining, and maintaining competitive integrated employment. The information and resources found in this guide include evidenced-based and promising practices, resources gathered from collaborative teams working across the country, and tools developed by federally funded national technical assistance centers. [This report was produced in partnership with Workforce Innovation Technical Assistance Center (WINTAC) and TransCen, Inc.]