The need for treatment and prevention of cardiovascular heart disease (CHD) cannot be overestimated. There have been attempts to treat and prevent CHD by focussing on the relationship between a psychosocial factor, Type A Behavior Pattern (TABP), and CHD. Recent research suggests a consistent relationship between hostility, (a characteristic previously attributed to TABP), and CHD, but an inconsistent relationship between hostility and TABP. Researchers now propose that hostility is the critical psychosocial factor associated with CHD. Absence of a sense of humor has also been proposed as a characteristic of TABP, and nonhostile sense of humor would seem to be incompatible with hostility. This study assessed the relationships among sense of humor, hostility, and TABP using multiple regression. Junior college students (N=151) were given four questionnaires: Jenkins Activity Survey, Situational Humor Response Questionnaire, Novacco Anger Scale, and a demographic questionnaire. Results suggest that hostility significantly accounts for about four percent of behavior pattern variance while sense of humor does not account for any variance. The meaning of the results pertaining to sense of humor is unclear since actual effect size was smaller than originally estimated and subsequent level of power was low. Counselors should note that while hostility reduction is appropriate for CHD treatment and prevention, humor has not yet been established as a suitable replacement. (Author/LLL)