Described are the development and field testing of programed instruction in orientation and mobility for 41 multiply handicapped blind students. Based on initial assessment on the Peabody Mobility Scale, it is explained that the students were prescribed individualized tasks in the areas of motor development, sensory skills, concept development and orientation and mobility skills. Examples are provided of the sequence formats which provide information on purpose, terminal objective, materials, prerequisites, activity objective, training activity, and recording procedures. It is reported that preliminary analyses of pretest-posttest differences in motor and sensory performance indicated a significant improvement by the experimental group using the programed instruction. (CL)