The study examined pre-, peri-, and neonatal factors in 271 British infants (weighing less than 1500 grams at birth), 188 of whom survived to 2 years. The study represented an attempt to define those factors which predict normal neurodevelopmental outcome in very low birth weight (VLBW) infants. Surviving infants were seen at 3, 6, 9, 12, and 24…

This symposium presentation outlines the activity of the Food and Drug Administration (FDA) in regulating the use during pregnancy and lactation of drugs which affect the fetus and neonate. When presented with an unexpected adverse effect of a drug or of a class of drugs, the FDA can take several steps. These steps include ordering total removal…

The behavior of the infant with prenatal drug exposure (PDE) is different from a nonexposed infant, and it is a difference that changes the rules of interaction for the caregiver. Infants exposed to opiates such as heroin or methadone demonstrate very specific signs of neurobehavioral dysfunction as they go through classic withdrawal symptoms.…

Statistics show that the improvement in the U.S. infant mortality rate began slowing down in 1981 and completely ended in 1985; this has been reflected in a significant increase in the percentage of infants born prematurely and with low birth weight. Increased attention is being given to the effects of maternal behavior during pregnancy, and…

This thesis discusses normal principles of infant development during the first 2 to 3 months of life and applies these principles to the provision of services to drug-exposed infants. Emphasis is on the infant as an active and interactive participant in his/her own development, the primacy of the body during this early developmental period, and…

Some of the principal research advances of the 1970s related to pregnancy and newborn infants and consequent changes in obstetrical practice are summarized in this report. The process of infant-parent attachment (bonding), adolescent pregnancy, and the reproductive hazards of tobacco, alcohol, and poor nutrition have been investigated and, in…

The effects of low, full (normal) and high birthweights on the broad range of neonatal behaviors measured by the Brazelton Neonatal Assessment Scale were investigated in a study which also attempted to replicate results of the authors' earlier study of the Brazelton Scale. Data from the original sample of 52 infants were included in the later…