Examined psychological and immunological changes among 25 caregivers of Alzheimer's disease (AD) patients, 25 caregivers of stroke patients, and 25 noncaregivers. Found that AD caregiving group was more psychologically distressed than stroke group, and both caregiving groups were more psychologically distressed than controls. Found no differences…

Examined caregiver listening responses as they occurred in conversations with an Alzheimer's patient. Videotaped 26 episodes of conversations between caregivers and patients in adult day health care setting. Found that sensitive listening and partial entry into the patient's frame (reality) may be effective response to prevent behavior and…

Developed Community Service Attitude Inventory (CSAI) to provide a measurement tool to further understanding of community service use by family caregivers of dementia patients. Testing of CSAI revealed five distinct components of family attitudes toward use of community services. (Author/NB)

Two interpretations of the Boston Naming Test (BNT) (E. Kaplan, H. Goodglass, and S. Weintraub, 1983) discontinuation rule of six consecutive failures were found in BNT use with 655 normal older adults and 140 people with Alzheimer's disease. Differences between lenient and rigorous interpretations of responses could have impact on…

Iowa nurses in long-term and home-health-care settings (n=53) were interested in continuing-education programs and teleconferences on the following Alzheimer's disease topics: challenging behaviors, family needs, case management, long-term care services, and new developments. Teleconferences were a viable strategy for isolated rural nurses. (SK)

Swedish nurse trainees (n=18) each followed a dementia patient through their training period. Themes emerged related to trainees' role as a personal guide. Creating a relationship with the patient and seeing the patient as a teacher were instructive experiences. (SK)

Examines differences in subjective psychological well-being between husband and wife caregivers of persons with Alzheimer's disease in comparison to the psychological states of noncaregiver spouses similar in age and ethnicity. Significant interactions for six out of nine psychological measures indicate that gender-related differences between…

Purpose: We examined the impact of caregiver neuroticism on longitudinal change in depression among spouse-caregivers of individuals with Alzheimer's disease receiving either enhanced psychosocial treatment or usual care. We were interested in whether high levels of caregiver neuroticism would lead to a diminished response to the enhanced…

This study examined the nature of verb deficits in 14 individuals with probable Alzheimer's Disease (PrAD) and nine with agrammatic aphasia. Production was tested, controlling both semantic and syntactic features of verbs, using noun and verb naming, sentence completion, and narrative tasks. Noun and verb comprehension and a grammaticality…

Impairment of hippocampal function precedes frontal and parietal cortex impairment in human Alzheimer's disease(AD). Neurotrophins are critical for behavioral performance and neuronal survival in AD. We used complex and radial mazes to assess spatial orientation and learning in wild-type and B6-Tg(ThylAPP)23Sdz (APP23) animals, a transgenic mouse…

ApoE gene polymorphism was examined in 100 adults with Down syndrome with and without dementia (Alzheimer's disease) and 346 control subjects. Additionally, a meta analysis of studies (total N=480 subjects) was performed. Results indicated a similar incidence of the gene across groups but subjects with the allele tended to an earlier onset of…

Caregivers (N=53) of dementia patients administered modified version of cognitive examination at home to their patients. Comparison between caregiver-administered and clinical examinations revealed high interrater reliability unaffected by caregiver age or education level. Reliable assessment of cognitive functioning by caregivers can provide…

Considered impact of physical environment on work-related stress and quality of care in day care center integrating demented people and other frail elderly. Examined positive and negative differences before and after move to new facility. Discusses implications for facility design and other program characteristics. (Author/CM)

Comparison of cognitive processes in 23 individuals with Down's syndrome (DS) and 23 individuals of comparable mental handicap without Down's syndrome found that older (above 40 years) DS subjects had significantly poorer outcomes. The areas of speech rate, number finding, and expressive attention appeared to show the earliest signs of dementia of…

Evaluated development of integrated family assessment inventory based on Double ABCX and Circumplex models of family functioning and its clinical utility with 121 primary family caregivers from cognitive disorders program. Proposed model predicted significant proportion of variance associated with caregiver stress and strain. Several aspects of…