Purpose: The Early Diagnosis Dyadic Intervention (EDDI) program provides a structured, time-limited protocol of one-on-one and dyadic counseling for family caregivers and care receivers who are in the early stages of dementia. The goals and procedures of EDDI are based on previous research suggesting that dyads would benefit from an intervention…

This study sought to develop an instrument for the assessment of grief in caregivers of persons with Alzheimer's disease. Study resulted in a 50-item scale containing three factors. Results suggest that caregiver grief is neither a unitary nor static construct and that a scale such as this may be appropriate for use in supportive, clinical, and…

A comparison of 12 persons with Parkinson's disease (PD), 12 with Alzheimer's disease (AD), and 12 in a control group on a memory scanning task found some slow scanning speed in PD patients. Despite normal scanning speed, most AD patients required highly structured instructions to complete the task, and many remained unable to do so. (SK)

The hypothesis that Alzheimer's disease (AD) degrades semantic representations predicts that AD qualitatively alters spontaneous thoughts. In two experiments contrasting free associations to words with strong (e.g., "bride-groom") versus weak (e.g., "body-leg") associates participants with AD produced less common responses (e.g., "bride-pretty")…

A newly developed quantitative near-infrared spectroscopy (NIRS) system was used to measure changes in cortical hemoglobin oxygenation during the Verbal Fluency Task in 32 healthy controls, 15 subjects with mild cognitive impairment (MCI), and 15 patients with Alzheimer's disease (AD). The amplitude of changes in the waveform, which was…

We report data from a group of patients with mild Alzheimer's disease on a range of tasks requiring either stored semantic knowledge about objects (e.g., naming object use) or the execution of action to objects (e.g., miming and using objects). We found that the patients were impaired at miming in response to objects, even when they could describe…

This study focused on one question: Do caregiver responses--emotion-focused coping, problem-focused coping, appraisal of burden, and appraisal of satisfaction--mediate or moderate the effects of caregiving stress on psychological well-being? Findings indicate that development of interventions that focus on how caregivers appraise their situation,…

Studied 127 informal caregivers of Alzheimer's disease patients to determine correlates of 5 components of burden as measured by Cost of Care Index. Significant relationships between predictor variables and burden components suggest that global scores and measures of burden do not identify specific problem areas relative to various components of…

A study of 133 control subjects and 141 with senile dementia of the Alzheimer type (SDAT) was designed to determine if language, motor planning, and memory were discrete components of performance. It found that patterns were highly individualized, which suggests that apraxia contributes significantly to dysfunction in some people with SDAT. (JOW)

Used an existential theoretical framework to guide the data interpretation in a qualitative study of 94 family caregivers of dementia patients. Results suggest that an existential framework provides an alternative paradigm for understanding the caregiving experience. (ABL)

Mutations in the amyloid precursor protein (APP) gene inducing abnormal processing and deposition of [beta]-amyloid protein in the brain have been implicated in the pathogenesis of Alzheimer's disease (AD). Although Tg2576 mice with the Swedish mutation ("hAPPswe") exhibit age-related [Alpha][beta]-plaque formation in brain regions like the…

Objective: To investigate the attitudes among mental health professionals regarding the use of genetic testing. Methods: Psychiatrists and other mental health professionals (N = 41) who were enrolled in a week-long course in psychiatric genomics completed questionnaires before and after the course designed to assess how diagnostic genetic tests…

The neuropathological correlates of suicide in older persons have received little research attention. Our recent study of elderly suicide victims from an Australian forensic medicine department (n = 143), unlike a previous case-control study, did not find an increased prevalence of Alzheimer's disease (AD) in older persons who committed suicide…

The home is clearly the major setting in which care is provided to individuals suffering from Alzheimer's disease. The Caring Home Program was a multi-disciplinary program designed to complement existing efforts to assist caregivers (N=12) with the in-home care of Alzheimer's disease patients. The program components consisted of an assessment of…

Interviewed five caregiving nursing staff members involved in dementia care concerning their ambivalent feelings toward spoon-feeding a severely demented patient. Although tube-feeding was regarded as an easier way to provide nourishment, spoon-feeding was preferred because it provided more human contact and love. (Author/NB)