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Showing 166 to 180 of 403 results Save | Export
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Cross, Katy; Smith, Edward E.; Grossman, Murray – Brain and Language, 2008
We examined the semantic impairment for natural kinds in patients with probable Alzheimer's disease (AD) and semantic dementia (SD) using an inductive reasoning paradigm. To learn about the relationships between natural kind exemplars and how these are distinguished from manufactured artifacts, subjects judged the strength of arguments such as…
Descriptors: Semantics, Alzheimers Disease, Dementia, Patients
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Chang, Yu-Ling; Bondi, Mark W.; Fennema-Notestine, Christine; McEvoy, Linda K.; Hagler, Donald J., Jr.; Jacobson, Mark W.; Dale, Anders M. – Neuropsychologia, 2010
Understanding the underlying qualitative features of memory deficits in mild cognitive impairment (MCI) can provide critical information for early detection of Alzheimer's disease (AD). This study sought to investigate the utility of both learning and retention measures in (a) the diagnosis of MCI, (b) predicting progression to AD, and (c)…
Descriptors: Control Groups, Alzheimers Disease, Correlation, Verbal Learning
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Colombo, Lucia; Fonti, Cristina; Stracciari, Andrea – Neuropsychologia, 2009
A group of 20 patients with probable Alzheimer disease (AD) and a control group were tested in a verb generation task, in a verb synonym task and several cognitive tests. Three types of verbs and novel verbs were presented in simple sentence frames, in two different conditions. In one condition participants were presented with the verb in the…
Descriptors: Control Groups, Semantics, Verbs, Alzheimers Disease
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Burgio, Louis D.; Collins, Irene B.; Schmid, Bettina; Wharton, Tracy; McCallum, Debra; DeCoster, Jamie – Gerontologist, 2009
Purpose: The aim of this study was to translate the evidence-based Resources for Enhancing Alzheimer's Caregiver Health (REACH) II intervention for use in 4 Area Agencies on Aging (AAAs). A secondary aim was to examine possible moderators of treatment outcome. Design and Methods: We used a quasi-experimental pre-post treatment design with no…
Descriptors: Alzheimers Disease, Caregivers, Intervention, Outcomes of Treatment
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Halpern, Andrea R.; Ly, Jenny; Elkin-Frankston, Seth; O'Connor, Margaret G. – Brain and Cognition, 2008
Two studies explored the stability of art preference in patients with Alzheimer's disease and age-matched control participants. Preferences for three different styles of paintings, displayed on art postcards, were examined over two sessions. Preference for specific paintings differed among individuals but AD and non-AD groups maintained about the…
Descriptors: Alzheimers Disease, Neurological Impairments, Patients, Art Products
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Chow, Maggie L.; Brambati, Simona M.; Gorno-Tempini, Maria Luisa; Miller, Bruce L.; Johnson, Julene K. – Brain and Cognition, 2010
Modern cognitive neuroscientific theories and empirical evidence suggest that brain structures involved in movement may be related to action-related semantic knowledge. To test this hypothesis, we examined the naming of environmental sounds in patients with corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), two…
Descriptors: Semantics, Alzheimers Disease, Diseases, Cerebral Palsy
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Wu, Lihui; Qiu, Zhuoying; Wong, Daniel; Hernandez, Lucy Wong; Zhao, Qianlei – Research in Developmental Disabilities: A Multidisciplinary Journal, 2010
Intellectual disability (ID) is a prevalent form of non-progressive cognitive impairment. The objectives of this articles are: to analyze the changes of ID in China, including its definition, prevalence, rehabilitation, education, vocational development, social life and support services; to review and to compare the issues of intellectual…
Descriptors: Social Life, Social Integration, Incidence, Mental Retardation
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Kelsey, Susan G.; Laditka, Sarah B.; Laditka, James N. – Gerontologist, 2010
Purpose: This study examines transitioning residents with Alzheimer's disease or a related disorder (ADRD) from assisted living facilities (ALFs) to memory care units (MCUs) from the perspective of 3 ALF organizational models: freestanding ALFs, ALFs with MCUs, and ALFs in continuing care retirement communities (CCRCs) with MCUs. Design and…
Descriptors: Grounded Theory, Alzheimers Disease, Older Adults, Memory
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Carpenter, Brian D.; Balsis, Steve; Otilingam, Poorni G.; Hanson, Priya K.; Gatz, Margaret – Gerontologist, 2009
Purpose: This study provides preliminary evidence for the acceptability, reliability, and validity of the new Alzheimer's Disease Knowledge Scale (ADKS), a content and psychometric update to the Alzheimer's Disease Knowledge Test. Design and Methods: Traditional scale development methods were used to generate items and evaluate their psychometric…
Descriptors: Alzheimers Disease, Caregivers, Risk, Patients
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Ewers, Michael; Zhong, Zhenyu; Burger, Katharina; Wallin, Anders; Blennow, Kaj; Teipel, Stefan J.; Shen, Yong; Hampel, Harald – Brain, 2008
The Apolipoprotein (ApoE) [epsilon]4 allele is a major genetic risk factor of Alzheimer's disease, and may affect the production of amyloid beta (A[beta][subscript 1-42]). Recently, we have shown that [beta]-secretase (BACE 1) activity can be reliably detected within the brain and human CSF. Here, we have examined an association between the ApoE…
Descriptors: Alzheimers Disease, Risk, Patients, Neurological Impairments
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Lombardi, Luigi; Sartori, Giuseppe – Journal of Memory and Language, 2007
Semantic features have different levels of importance in indexing a target concept. The article proposes that semantic relevance, an algorithmically derived measure based on concept descriptions, may efficiently capture the relative importance of different semantic features. Three models of how semantic features are integrated in terms of…
Descriptors: Models, Semantics, Memory, Cues
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Waring, Jill D.; Chong, Hyemi; Wolk, David A.; Budson, Andrew E. – Brain and Cognition, 2008
Patients with mild Alzheimer's disease (AD) display a greater tendency to endorse unstudied items as "old" on memory tests than healthy older adults. This liberal response bias may result in mistaken beliefs about the completion of common tasks. This research attempted to determine whether it was possible to shift the response bias of mild AD…
Descriptors: Response Style (Tests), Alzheimers Disease, Patients, Recognition (Psychology)
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Oremus, Mark; Wolfson, Christina; Bergman, Howard; Vandal, Alain C. – Canadian Journal on Aging, 2007
Physicians (N=803) were contacted via postal survey and given two sets of efficacy measures for drug treatments in Alzheimer's disease: (a) the time that patients spend in a mild or moderate state of disease; (b) levels of modification to disease progression in the areas of cognition, behaviour, and mood, and ability to perform basic activities of…
Descriptors: Patients, Physicians, Alzheimers Disease, Surveys
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Villemagne, V. L.; Pike, K. E.; Darby, D.; Maruff, P.; Savage, G.; Ng, S.; Ackermann, U.; Cowie, T. F.; Currie, J.; Chan, S. G.; Jones, G.; Tochon-Danguy, H.; O'Keefe, G.; Masters, C. L.; Rowe, C. C. – Neuropsychologia, 2008
Approximately 30% of healthy persons aged over 75 years show A[beta] deposition at autopsy. It is postulated that this represents preclinical Alzheimer's disease (AD). We evaluated the relationship between A[beta] burden as assessed by PiB PET and cognitive decline in a well-characterized, non-demented, elderly cohort. PiB PET studies and…
Descriptors: Alzheimers Disease, Cognitive Tests, Older Adults, Memory
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Garbutt, Siobhan; Matlin, Alisa; Hellmuth, Joanna; Schenk, Ana K.; Johnson, Julene K.; Rosen, Howard; Dean, David; Kramer, Joel; Neuhaus, John; Miller, Bruce L.; Lisberger, Stephen G.; Boxer, Adam L. – Brain, 2008
Frontotemporal lobar degeneration (FTLD) often overlaps clinically with corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP), both of which have prominent eye movement abnormalities. To investigate the ability of oculomotor performance to differentiate between FTLD, Alzheimer's disease, CBS and PSP, saccades and smooth pursuit were…
Descriptors: Neurological Impairments, Alzheimers Disease, Eye Movements, Dementia
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