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Luhnen, Miriam; Prediger, Barbara; Neugebauer, Edmund A. M.; Mathes, Tim – Research Synthesis Methods, 2019
Introduction: The number of systematic reviews of health economic evaluations (SR-HEs) is increasing. We aimed at providing a detailed overview of the characteristics and applied methods in recently published SR-HEs. Methods: We searched MEDLINE (03/2017) for SR-HEs published since 2015 using validated search filters. We included studies that…
Descriptors: Economics, Databases, Medical Research, Search Strategies
Mathes, Tim; Kuss, Oliver – Research Synthesis Methods, 2018
Meta-analyses often include only a small number of studies ([less than or equal to]5). Estimating between-study heterogeneity is difficult in this situation. An inaccurate estimation of heterogeneity can result in biased effect estimates and too narrow confidence intervals. The beta-binominal model has shown good statistical properties for…
Descriptors: Comparative Analysis, Meta Analysis, Probability, Statistical Analysis