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Direct linkRemiro-Azócar, Antonio; Heath, Anna; Baio, Gianluca – Research Synthesis Methods, 2022
Population adjustment methods such as matching-adjusted indirect comparison (MAIC) are increasingly used to compare marginal treatment effects when there are cross-trial differences in effect modifiers and limited patient-level data. MAIC is based on propensity score weighting, which is sensitive to poor covariate overlap and cannot extrapolate…
Descriptors: Patients, Medical Research, Comparative Analysis, Outcomes of Treatment
