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Siegel, Lianne; Murad, M. Hassan; Chu, Haitao – Research Synthesis Methods, 2021
Often clinicians are interested in determining whether a subject's measurement falls within a normal range, defined as a range of values of a continuous outcome which contains some proportion (eg, 95%) of measurements from a healthy population. Several studies in the biomedical field have estimated reference ranges based on a meta-analysis of…
Descriptors: Meta Analysis, Medical Research, Biomedicine, Bayesian Statistics
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Shi, Jiandong; Luo, Dehui; Weng, Hong; Zeng, Xian-Tao; Lin, Lu; Chu, Haitao; Tong, Tiejun – Research Synthesis Methods, 2020
When reporting the results of clinical studies, some researchers may choose the five-number summary (including the sample median, the first and third quartiles, and the minimum and maximum values) rather than the sample mean and standard deviation (SD), particularly for skewed data. For these studies, when included in a meta-analysis, it is often…
Descriptors: Statistics, Computation, Sample Size, Mathematical Formulas
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Hong, Hwanhee; Chu, Haitao; Zhang, Jing; Carlin, Bradley P. – Research Synthesis Methods, 2016
Bayesian statistical approaches to mixed treatment comparisons (MTCs) are becoming more popular because of their flexibility and interpretability. Many randomized clinical trials report multiple outcomes with possible inherent correlations. Moreover, MTC data are typically sparse (although richer than standard meta-analysis, comparing only two…
Descriptors: Bayesian Statistics, Meta Analysis, Outcomes of Treatment, Comparative Analysis