The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…

Biomedical data science education faces the challenge of preparing students for conducting rigorous research with increasingly complex and large datasets. At the same time, philosophers of science face the challenge of making their expertise accessible for scientists in such a way that it can improve everyday research practice. Here, we…

Transcription is the critical first step in expressing a gene, during which an RNA polymerase (RNAP) synthesizes an RNA copy of one strand of the DNA that encodes a gene. Here we describe a laboratory experiment that uses a single assay to probe two important steps in transcription: (1) RNAP binding to DNA, and (2) the transcriptional activity of…

The central argument of this article is that abduction as a "mode of inference" is a key element in the nature of scientists' science and should consequently be introduced in school science. Abduction generally understood as generation and selection of hypotheses permits to articulate the classical scientific contexts of discovery and…

The COVID-19 pandemic provides an opportunity for teachers to explicitly address nature of science (NOS) themes during instruction. Aligned with key NOS categories in the "Next Generation Science Standards," this article discusses events and trends from the pandemic that teachers can use to help students understand values and methods of…

Aragón, Acevedo-Díaz and García-Carmona study prospective biology teachers' understanding of the Nature of Science (NOS). In my comment, I would first like to step back and ask "what it is to understand something", i.e. the sciences. I will turn to a quasi-Wittgensteinian epistemological tradition and suggest that, contrary to our habit…

Despite advances in discussions about the nature of science, there is still a paucity of discussion on the ontological dimension of science in science education research that makes it difficult to defend its content and teaching. In this article, the reasons for trusting science and science education are analyzed through three arguments. The first…

While computer simulations are a key element in understanding and doing science today, their nature and implications for science education have not been adequately explored in the relevant literature. In this article, (1) we provide an analysis of the methodology and epistemology of computer simulations, aiming to contribute to a sound and…

The social reaction to the recent detection of the Higgs boson and gravitational waves provided evidence that public interest in modern physics has reached a high point. Although these modern physics topics are being introduced into the upper secondary physics curricula in a growing number of countries, their potential for teaching various aspects…

The authors conducted a qualitative content analysis of the 400 National Science Teachers Association Outstanding Science Trade Books for Students K-12 from 2010-2017 selected for their instructional usefulness in science classrooms. The authors examined these expert-recommended science trade books to better understand their design and to identify…

Teaching false theories goes against the general pedagogical and philosophical belief that we must only teach and learn what is true. In general, the goal of pedagogy is taken to be epistemic: to gain knowledge and avoid ignorance. In this article, I argue that for realists and antirealists alike, epistemological and pedagogical goals have to come…

In this article, I explore the tension between the current political context in which science needs defending against anti-intellectualism and outright assaults on evidence as a means of decision-making on the one hand and the overzealous scientism that can result from backlash against a perceived lack of rigor in various forms of inquiry. To do…

When the sun rose over America on July 4, 2012, the world of science had radically changed. The Higgs boson had been discovered. Mind you, the press releases were more cautious than that, with "a new particle consistent with being the Higgs boson" being the carefully constructed phrase of the day. But, make no mistake, champagne corks…

Student reasoning about cases of natural selection is often plagued by errors that stem from miscategorising selection as a direct, causal process, misunderstanding the role of randomness, and from the intuitive ideas of intentionality, teleology and essentialism. The common thread throughout many of these reasoning errors is a failure to apply…

Truth is for sale today, some critics claim. The increased commodification of science corrupts it, scientific fraud is rampant and the age-old trust in science is shattered. This cynical view, although gaining in prominence, does not explain very well the surprising motivation and integrity that is still central to the scientific life. Although…