Metabolic Control Analysis (MCA) is a systems biology approach that measures the control of a metabolic step on the overall flux of a metabolic pathway. In undergraduate courses in biochemistry, learning of MCA can be encouraged by experimental activities demonstrating practical applications of the MCA theory. In this work, we present a laboratory…

Multistep synthesis is a key capstone experience in organic laboratory instruction. Here, a four-step synthesis of avobenzone, an active component in sunscreens, has been developed that can be completed in two 4 h laboratory periods. This synthesis incorporates green principles and includes an aldol condensation, electrophilic addition of bromine…

A multistep synthesis of a novel arylidene 3­(2"H")-furanone has been designed and optimized for the second-year organic laboratory. The three-step sequence consists of a nucleophilic substitution, intramolecular cyclization, and acid-catalyzed aldol condensation, and can be carried out within two 3 h laboratory periods. The final…

Organizing undergraduates in chemistry, energy engineering, and chemical engineering specialties to participate in an energy transformation experiment can encourage them to think about the impact of human activities on nature and stimulate them to learn more about the topic. This laboratory experiment demonstrates a general approach to the…

This experimental lab set is for students taking college chemistry courses. It includes four laboratory works and completely illustrates the important parts of chemical kinetics, namely the determination of the rate constant and the determination of the factors influencing its value. They can be used in a laboratory set for a physical chemistry…

Williamson ether experiments are commonly performed by students in undergraduate organic chemistry instructional laboratory courses. In this multioutcome experiment, students were provided 4-bromophenol and one of three alkyl halides: 1-bromopentane, 1-bromobutane, or 1-bromo-3-methylbutane. The alkyl halides served as the unknown component of the…

An experiment was developed for a first year food chemistry laboratory course that demonstrates the influence of several aspects of polysacharide structure on the rate of amylase catalyzed hydrolysis. The experiment would be particularly well-suited to a first year chemistry course that was targeted at nonchemistry majors, such as health related…

Scientific laboratories are among the most challenging course components to integrate into online instruction. Available technology restricts the design and nature of experiments, and it can be hard to replicate the collaborative lab environment where frequent and immediate instructor feedback is the norm. Here we report on technological and…

Mass spectrometers are ever-increasingly powerful, user-friendly, and affordable. Thus, the addition of mass spectrometry experiments into the undergraduate laboratory curriculum is now both feasible and an effective tool to introduce students to relevant instrumentation. Here an experiment demonstrating the use of a high-resolution electrospray…

This communication describes an updated experiment of peptide synthesis, involving determination of the loading capacity of a Fmoc-protected amino functionalized resin using UV-vis spectroscopy and a subsequent synthesis of a dipeptide in order to exemplify the experimental solid-phase synthesis procedure as an alternative technique in organic…

Flavonoids have been studied extensively for their antioxidant properties. Specifically, the flavonoids in tea, such as catechin and epigallocatechin gallate, have been shown to have positive health effects. These compounds are also oxidizable, so the concentrations of these compounds in a given kind of tea can be determined using cyclic…

Different virtual chemistry laboratories (VCLs) have been developed with which students can perform and practice their practical and experimental work, thus increasing their learning before performing the same work in a real chemistry laboratory. In this paper, we present an analysis of the existing virtual chemistry laboratories by identifying…

As an outcome of multidiscipline integration, the polymeric surfactant is of growing importance in modern industry and scientific research. However, the instructional introduction on polymeric surfactants is still insufficient in universities nowadays. In order to effectively guide undergraduates to study polymeric surfactant, a new polymeric…

During the COVID-19 pandemic, an at-home enzyme assay was developed for a biochemistry laboratory course at Arizona State University. The experiment was designed to use items that could be easily obtained and safe to use. The experiment focused on the analysis of salivary amylase using starch from food as a substrate, black tea as an inhibitor,…

The natural sciences, by their very nature, are based on the exploration of the physical world, and digital mobile devices are considered appropriate to support this exploration (Suárez et al., 2018) since they offer the tools that make this investigation more accessible but also ubiquitous (Crompton et al., 2017). Inquiry-based learning is a…