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Review of the Plausibility of Iron Deficiency Hypothesis of Autism
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Aaron Grossman – Review Journal of Autism and Developmental Disorders, 2017
Iron consumption among mothers has recently been found to decrease the risk of autism in offspring. However, epidemiological evidence of an increasing iron deficiency among mothers or infants is lacking, and evidence within an individual-level framework of iron deficiency confers doubt upon iron's role as a direct cause of autism. We attempt to…
Descriptors: Autism Spectrum Disorders, Mothers, Pregnancy, Prenatal Influences
Prenatal and Early Life Risk Factors of Schizophrenia
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Lattari, Fallon; Dragowski, Eliza A. – Communique, 2011
Childhood-onset schizophrenia is an exceedingly rare mental illness whose complex, multifaceted behavioral presentation can disrupt child development and raise diagnostic and treatment difficulties for attending clinicians. The disorder, affecting one in 30,000 children, shares the same diagnostic criteria and symptoms as its adult counterpart,…
Descriptors: Schizophrenia, Symptoms (Individual Disorders), Child Development, At Risk Persons
Pre- and Peri-Natal Environmental Risks for Attention-Deficit Hyperactivity Disorder (ADHD): The Potential Role of Epigenetic Processes in Mediating Susceptibility
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Mill, Jonathan; Petronis, Arturas – Journal of Child Psychology and Psychiatry, 2008
Attention-deficit hyperactivity disorder (ADHD) is a common childhood neurobehavioural disorder defined by symptoms of developmentally inappropriate inattention, impulsivity and hyperactivity. As is the norm for most psychiatric phenotypes, traditional aetiological studies have focused primarily on the interplay between genetic and environmental…
Descriptors: Attention Deficit Hyperactivity Disorder, Child Behavior, Behavior Problems, Environmental Influences
The Dopamine Receptor D4 7-Repeat Allele and Prenatal Smoking in ADHD-Affected Children and Their Unaffected Siblings: No Gene-Environment Interaction
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Altink, Marieke E.; Arias-Vasquez, Alejandro; Franke, Barbara; Slaats-Willemse, Dorine I. E.; Buschgens, Cathelijne J. M.; Rommelse, Nanda N. J.; Fliers, Ellen A.; Anney, Richard; Brookes, Keeley-Joanne; Chen, Wai; Gill, Michael; Mulligan, Aisling; Sonuga-Barke, Edmund; Thompson, Margaret; Sergeant, Joseph A.; Faraone, Stephen V.; Asherson, Philip; Buitelaar, Jan K. – Journal of Child Psychology and Psychiatry, 2008
Background: The dopamine receptor D4 ("DRD4") 7-repeat allele and maternal smoking during pregnancy are both considered as risk factors in the aetiology of attention deficit hyperactivity disorder (ADHD), but few studies have been conducted on their interactive effects in causing ADHD. The purpose of this study is to examine the gene by…
Descriptors: Siblings, Smoking, Attention Deficit Hyperactivity Disorder, Pregnancy
Intervention for Individuals with Fetal Alcohol Spectrum Disorders: Treatment Approaches and Case Management
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Paley, Blair; O'Connor, Mary J. – Developmental Disabilities Research Reviews, 2009
Exposure to alcohol in utero is considered to be the leading cause of developmental disabilities of known etiology. The most severe consequence of such exposure, fetal alcohol syndrome (FAS), is characterized by a distinct constellation of characteristic facial anomalies, growth retardation, and central nervous system (CNS) dysfunction. Some…
Descriptors: Developmental Disabilities, Fetal Alcohol Syndrome, Etiology, Anatomy
Timing of Prenatal Stressors and Autism
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Beversdorf, D. Q.; Manning, S. E.; Hillier, A.; Anderson, S. L.; Nordgren, R. E.; Walters, S. E.; Nagaraja, H. N.; Cooley, W. C.; Gaelic, S. E.; Bauman, M. L. – Journal of Autism and Developmental Disorders, 2005
Recent evidence supports a role for genetics in autism, but other findings are difficult to reconcile with a purely genetic cause. Pathological changes in the cerebellum in autism are thought to correspond to an event before 30-32 weeks gestation. Our purpose was to determine whether there is an increased incidence of stressors in autism before…
Descriptors: Autism, Genetics, Etiology, Brain
Effect of Maternal Rubella on Hearing and Vision: A Twenty Year Post-Epidemic Study.
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Johnson, Donald D.; Whitehead, Robert L. – American Annals of the Deaf, 1989
Two groups of deaf college students, including 104 deaf from congenital rubella syndrome (CRS) and 138 deaf from other reasons, received complete audiometric assessments and ophthalmological examinations. Degree of hearing loss did not differ between groups. However, 7 visual problems were found to be more prevalent with the CRS population.…
Descriptors: College Students, Comparative Analysis, Deafness, Epidemiology
Advanced Microscopic Imaging Methods to Investigate Cortical Development and the Etiology of Mental Retardation
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Haydar, Tarik F. – Mental Retardation and Developmental Disabilities Research Reviews, 2005
Studies on human patients and animal models of disease have shown that disruptions in prenatal and early postnatal brain development are a root cause of mental retardation. Since proper brain development is achieved by a strict spatiotemporal control of neurogenesis, cell migration, and patterning of synapses, abnormalities in one or more of these…
Descriptors: Mental Retardation, Patients, Etiology, Brain