An estimated 2.5 million people worldwide are living with multiple sclerosis (MS), and this disease may be increasing in prevalence. MS is a disease of the central nervous system that is associated with heterogeneous symptoms and functional consequences, and the current first-line disease-modifying therapies often become ineffective later in the…

In the United States, there are more than 14 million cancer survivors. Many of these survivors have been treated with multimodal therapy including surgery, radiation therapy, chemotherapy, and targeted therapies. These therapies improve survival; however, they also cause acute and chronic side effects that can undermine health and quality of life.…

Challenges that face the academic research enterprise are numerous. These concerns include, but are not limited to: declines in extramural funding for investigatorinitiated research, an aging faculty workforce (the average age of securing a faculty's first R01 is over 42), insufficient funds to support faculty laboratories, and limited access to…

On the surface, a gathering held for young research faculty last week at Cold Spring Harbor Laboratory was a clear expression of determination by the National Institutes of Health (NIH) to help them compete for grants. The agency fears that continued Congressional budget cuts, combined with the growing number of scientists who work later into…

What works to increase success for Latinos in colleges and universities? Since 2005, Examples of Excelencia has been the only national effort to recognize evidence-based practices that accelerate Latino student success in higher education. Through this process, "Excelencia" recognizes programs in three different academic levels as well…

The purpose of this literature review was to provide an overview of the research on gastrointestinal (GI) symptoms in autism spectrum disorder. Topics explored include the prevalence of GI symptoms, the importance of studying GI symptoms, the difficulties in diagnosis, as well as the questionnaire measures used to assess gastrointestinal symptoms.…

Roughly 40% of the sizeable medical research and literature on recently approved drugs is "ghost managed" by the pharmaceutical industry and its agents. Research is performed and articles are written by companies and their agents, though apparently independent academics serve as authors on the publications. Similarly, the industry hires academic…

In the current era of limited funding, researchers need strategic alliances to launch or sustain programs of research to significantly impact the nation's health. This article presents a collaborative model, the Scholar Award Model, which is based on a strategic alliance between a College of Nursing in a research-intensive university and a…

Data from a cough challenge study are displayed with dot charts to demonstrate the importance of graphs in understanding data, principles of graph construction and visual perception. The data are available for use in the classroom.

We consider the effect on estimation of simultaneous variable centering and interaction effects in linear regression. We technically define, review, and amplify many of the statistical issues for interaction models with centering in order to create a useful and compact reference for teachers, students, and applied researchers. In addition, we…

Hampton University President William Harvey's initial readings of proton therapy for cancer sparked his interest. Within a few months, Dr. Harvey was assigning widely respected Hampton nuclear physicist Dr. Cynthia Keppel to do more exploration. Today, the new $225 million Hampton University Proton Therapy Institute, one of eight therapy sites in…

The Mayo Innovation Scholars Program introduces undergraduates to technology transfer in biomedical sciences by having teams of students from multiple disciplines (e.g., biology, chemistry, economics, and business) analyze inventions in development at the Mayo Clinic. Over 6 months, teams consult with inventors, intellectual property experts, and…

These are interesting days in the scientific, social, and political debates about human embryonic stem cell research. Pluripotent stem cells--cells that can, in principle, give rise to the body's full range of cell types--were previously derivable only from human embryos that were destroyed in the process. Now, a variety of somatic cell types can…

When representatives of the National Library of Medicine (NLM), a tiny unit of the federal government's massive National Institutes of Health in Bethesda, Md., began an education program several years ago to help residents of indigenous communities improve their access to health care information and resources, they found a surprise along the way.…

Heightened commercialism on campus is pulling universities and their faculties away from higher education's core commitment to academic research, teaching, and the production of reliable public knowledge. Nearly a century ago, similar threats led to the birth of a new faculty organization--the American Association of University Professors…