This laboratory experiment offers a research-style experience designed for senior undergraduate students in a multidisciplinary laboratory setting. The experiment focuses on the synthesis, characterization, and application of a cation-exchange membrane made of COF-SO[subscript 3]Na/PAN for ion separation. By participating in this practical session, students gain firsthand experience in both the fundamental procedures of membrane synthesis and the application of widely recognized scientific research methodologies. Furthermore, the experiment offers students hands-on opportunities to become acquainted with modern instrumental techniques extensively used in chemical research, such as Fourier-transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), and scanning electron microscopy (SEM) analysis. The acquisition of these skills not only provides students with valuable practical experience but also equips them with the ability to effectively communicate their future research accomplishments to the broader scientific community. Moreover, the experiment demonstrates the significant potential of the synthesized membrane material for real-world applications, as evidenced by its effectiveness in osmotic energy extraction through ion separation using reverse electrodialysis (RED). This serves to underscore the practical utility of the research findings and reinforces students' understanding of the broader implications of materials chemistry. It also enables instructors to contextualize the experiment within the broader field, encouraging students to explore the frontiers of knowledge and innovation.