This article explores an inventive approach to teaching physiology that blends the use of the Notability app on the iPad with video-based learning to visually explain intricate physiological concepts in real time. The core idea is to offer students a more dynamic and interactive way to comprehend complex physiological concepts during review sessions and outside of class. Students actively participated by creating their own drawings and asking questions throughout each review session. At the end of these review sessions, students could obtain a copy of the Notability file from the professor. Additionally, a series of concise instructional videos were developed, where the professor explained physiological concepts by creating a diagram using Notability while simultaneously explaining the specific physiological process. These videos were then posted on Canvas, which allowed students the opportunity to review them at their convenience. Students self-reported increased understanding of the material. To gauge the effectiveness of this teaching approach, exam scores were analyzed. Students scored higher on questions related to topics with associated Notability videos compared to those without. These findings provide evidence that this novel teaching method improves student engagement and comprehension in physiology courses by leveraging technology, active participation, and visual aids to create an enriched learning experience. Ultimately, this helped improve student performance and understanding of complex physiological concepts.