Discusses the structure and function of the liver protein cytochrome P-450, an important catalyst for a variety of detoxification reactions. Diagnostic substracts for this heme-containing monooxygenase, synthetic modes of the active site, and oxidations with synthetic metalloporphyrins are the major topic areas considered. (JN)

Biomimetic chemistry is concerned with the synthesis of small, molecular weight molecules which mimic the properties of metal-containing sites within certain biologically significant species. A series of experiments for an advanced undergraduate laboratory is described as a way to introduce this area into the chemistry curriculum. (JN)

Oxidation kinetics in metals and the role defects play in diffusion-controlled reactions are discussed as background for a junior/senior-level experiment in the physical or inorganic chemistry laboratory. Procedures used and typical data obtained are provided for the experiment. (JN)

Discusses the differences between iron and copper. Describes various aspects of the behaviors of these two elements, including those of biological and environmental significance. Addresses the evolution of the atmosphere and sedimentary ore formation, the phylogeny of iron and copper, and some anthropological notes regarding the use of the metals.…

Considers three common cases of localized corrosion of metals: pitting, crevice, and stress corrosion. Provides experimental methods for studying all three methods. Includes a discussion of expected results. (ML)