Systematic reviews (SRs) have an important role in the healthcare decision-making practice. Assessing the overall confidence in the results of SRs using quality assessment tools, such as "A MeaSurement Tool to Assess Systematic Reviews 2" (AMSTAR 2), is crucial since not all SRs are conducted using the most rigorous methods. In this…

Reference intervals, or reference ranges, aid medical decision-making by containing a pre-specified proportion (e.g., 95%) of the measurements in a representative healthy population. We recently proposed three approaches for estimating a reference interval from a meta-analysis based on a random effects model: a frequentist approach, a Bayesian…

The goal of education and research in all disciplines is to develop critical thinking skills as a method for improving clinical decisionmaking. The emphasis on critical thinking is nothing new and can be traced back to ancient times when Socrates challenged his students to think about their knowledge, beliefs, and behaviors by interrogating them.…

When federal regulations governing human subjects research were modified, the State University of New York at Albany chose the consensual approach to revise its institutional policy. The process is described and its advantages and disadvantages are identified. (Author/MLW)

This article describes an innovative curriculum module the first author created on the two-way exchange between statistics and applied ethics. The module, having no particular mathematical prerequisites beyond high school algebra, is part of an undergraduate interdisciplinary ethics course which begins with a 3-week introduction to basic applied…

Many undergraduate medical curricula have been criticized for not adequately preparing graduates to be independent problem-solvers able to analyze clinical and published evidence. A program in the critical appraisal of medical literature at the University of Cincinnati School of Medicine is described. (MLW)

The role of Australia's National Health and Medical Research Council, an independent statutory body, in distribution of funds for research projects, programs, units, and major institutes. The agency's evaluation system, resource allocation practices, and training and career support system are described briefly. (MSE)