Proteins are "magical" workers inside our body, as they accomplish most of the cellular functions. Here we report on a novel approach to teach protein folding and unfolding, using magnets and flexible 3D-printed protein structures. To illustrate this physical process, we used colored circular magnets designed for whiteboards, connected…

Increasingly, students training in the biological sciences depend on a proper grounding in biological statistics, data science and experimental design. As biological datasets increase in size and complexity, transparent data management and analytical methods are essential skills for undergraduate biologists. We propose that using the software R…

A discovery-based Grignard experiment for a second-year undergraduate organic chemistry course is described. The exclusive Grignard reagent formed by the reaction of 1-bromo-4-fluorobenzene (1) with Mg is 4-fluorophenylmagnesium bromide (2), which is treated with either benzophenone or CO[subscript 2] to produce the corresponding fluorinated…

In this experiment for an introductory undergraduate organic chemistry lab, students tetraalkylate tertbutylcalix[4]arene, a bowl-shaped macrocyclic oligophenol, and examine the supramolecular chemistry of the tetraether product by proton nuclear magnetic resonance (NMR) spectroscopy. Complexation with a sodium ion reduces the conformational…

Graphene's unique combination of exceptional mechanical, electronic, and thermal properties makes this material a promising candidate to enable next-generation technologies in a wide range of fields, including electronics, energy, and medicine. However, educational activities involving graphene have been limited due to the high expense and…

A laboratory experiment is described in which students compare two methods for the determination of the calcium content of commercial dietary supplement tablets. In a two-week sequence, the sample tablets are first analyzed via complexometric titration with ethylenediaminetetraacetic acid and then, following ion exchange of the calcium ion present…

This article presents a hybrid methodological technique that fuses elements of experimental design with qualitative strategies to explore mediated communication. Called the "qualitative experiment," this strategy uses focus groups and in-depth interviews "within" randomized stimulus conditions typically associated with…

We describe here two open-ended laboratory investigations for an undergraduate laboratory course that uses students' DNA as templates for quantitative real-time PCR and for traditional PCR followed by RFLP analysis. Students are captivated by the immediacy of the application and the relevance of the genotypes and traits, lactase persistence or…

Computers have changed the landscape of scientific research in profound ways. Technology has always played an important role in scientific experimentation--through the development of increasingly sophisticated tools, the measurement of elusive quantities, and the processing of large amounts of data. However, the advent of social networking and the…

Science education blogs can serve as powerful digital lab notebooks that contain text, images, and videos. Each blog entry documents a moment in time, but becomes interactive with the addition of readers' comments. Blogs can provide a realistic experience of the peer-review process and generate evolving descriptions of observations through time.…

Investigations with Wisconsin Fast Plants can make the subject matter come alive...or dead, depending on the experimental treatment. This became apparent when a university-based teacher educator and a fifth-grade teacher collaborated on a professional development experience aimed at increasing understanding of how science inquiry could be used…