Educational design research (EDR) was applied to address the challenge of providing more public health professionals with opportunities to develop their knowledge and skills related to Good Clinical Practices (GCP) inspections. The conduct of clinical research in accordance with the principles of GCP is necessary to ensure that clinical research…

As the burden of noncommunicable diseases (NCDs) rises in settings with an equally high burden of infectious diseases in the Global South, a new sense of urgency has developed around research capacity building to promote more effective and sustainable public health and health care systems. In 2010, NCDs accounted for more than 2.06 million deaths…

Objective: Identify the most performant automated text classification method (eg, algorithm) for differentiating empirical studies from nonempirical works in order to facilitate systematic mixed studies reviews. Methods: The algorithms were trained and validated with 8050 database records, which had previously been manually categorized as…

Background: Stratified medicine seeks to identify patients most likely to respond to treatment. Individual participant data (IPD) network meta-analysis (NMA) models have greater power than individual trials to identify treatment-covariate interactions (TCIs). Treatment-covariate interactions contain "within" and "across" trial…

Black participants remain significantly underrepresented in clinical research. Mistrust in medical researchers has been named a key barrier to the successful enrollment of minority study participants. However, trust is a social--interactional construct, and its effects on behavior are complex. This study hypothesized that intention to participate…

Purpose: Overuse injuries are common in sport, but complete understanding of injury risk factors remains incomplete. Although biomechanical studies frequently examine musculoskeletal injury mechanisms, human movement variability studies aim to better understand neuromotor functioning, with proposed connections between overuse injury mechanisms and…

National and institutional policies to escalate the production of doctorates have raised concerns about the quality of PhDs in South Africa. This study evaluates examiner reports of doctorates by thesis and publication in clinical medicine to ascertain the criteria that examiners used to define a successful doctoral thesis. A qualitative…

Network meta-analysis is used to simultaneously compare multiple treatments in a single analysis. However, network meta-analyses may exhibit inconsistency, where direct and different forms of indirect evidence are not in agreement with each other, even after allowing for between-study heterogeneity. Models for network meta-analysis with random…

There is much more to science education than the requirements demanded by the examination curriculum. This article illustrates one example of an in-depth investigation, kick started with a Royal Society Partnership Grant, into essential oils as antimicrobial agents. The project and subsequent extensions were selected to be presented at various…

Evidence-based practice (EBP) is the norm and expectation for providing interventions in school psychology. However, there are two major hurdles to be addressed before EBP can be a true improvement in providing educational and psychological interventions to children and families. The first challenge is that the standard of clinical research limits…

This study aimed to examine the behaviour of learners across a whole system and in various courses to reveal the interrelation between learners' system interaction, age, programme features and course design. We obtained data from the system logs of 1,634 learners enrolled in distance learning programmes. We performed hierarchical clustering…

Medicine is a science dealing with uncertainty and the art of judging probability. For effective communication, doctors, researchers, or health sciences writers, need to master the use of modality whereby unreal situations can be discussed. How modal verbs -- the most commonly used type of modality applied in the writing of health and medical…

STEM-related educational outreach offers students enriching opportunities to become more familiar with science, in terms of how it relates to their daily lives and with respect to possible career paths that they might want to follow. At the same time, graduate student trainees providing that outreach act as important resources for elementary and…

When conducting research synthesis, the collection of studies that will be combined often do not measure the same set of variables, which creates missing data. When the studies to combine are longitudinal, missing data can occur on the observation-level (time-varying) or the subject-level (non-time-varying). Traditionally, the focus of missing…

Meta-analysis can necessitate the combination of parallel and cross-over trial designs. Because of the differences in the trial designs and potential biases notably associated with the crossover trials, one often combines trials of the same designs only, which decreases the power of the meta-analysis. To combine results of clinical trials from…