The Hartung-Knapp method for random-effects meta-analysis, that was also independently proposed by Sidik and Jonkman, is becoming advocated for general use. This method has previously been justified by taking all estimated variances as known and using a different pivotal quantity to the more conventional one when making inferences about the…

Having surveyed the history and methods of meta-regression in a previous paper, in this paper, we review which and how meta-regression methods are applied in recent research syntheses. To do so, we reviewed studies published in 2016 across four leading research synthesis journals: "Psychological Bulletin," the "Journal of Applied…

Introduction: The number of systematic reviews of health economic evaluations (SR-HEs) is increasing. We aimed at providing a detailed overview of the characteristics and applied methods in recently published SR-HEs. Methods: We searched MEDLINE (03/2017) for SR-HEs published since 2015 using validated search filters. We included studies that…

Background: Both PubMed and Ovid MEDLINE contain records from the MEDLINE database. However, there are subtle differences in content, functionality, and search syntax between the two. There are many instances in which researchers may wish to search both interfaces, such as when conducting supplementary searching for a systematic review to retrieve…

Objective: This study aimed to assess the effects of eXamining Relevance of Articles to Young Survivors (XRAYS), an online resource that provides brief articles discussing recent research relevant to young women with or at risk for breast cancer, on users' knowledge about information covered in media reports. An evaluator also assessed the degree…

Biomedical research policy in many countries has adopted the principle of active involvement in research. However, how different approaches to involvement such as patient and public involvement/engagement (PPIE), qualitative research, participatory research, co-design and co-production sit alongside each other, is contentious and unclear. There…

This article provides responses from academic neurologist Navid Seraji-Bozorgzad to questions posed by Don Ambrose. After moving from Iran to the United States in 1984, Navid Seraji-Bozorgzad attended The Roeper School in Bloomfield Hills, Michigan for high school. He studied physics as an undergraduate at the University of Michigan. After…

With the ongoing and expanding use of willed bodies in medical education and research, there has been a concomitant rise in the need for willed bodies and an increase in the means of supplying these bodies. A relatively recent development to enlarge this supply has been the growth of for-profit willed body companies ("body brokers") in…

Racial bias in research impacts a study's relevancy, validity and reliability, though presently this aspect is not addressed in critical appraisal tools, and consequently appraisers may not take racial bias into account when assessing a paper's quality. Drawing on critical race theory (CRT) tenets that racism is ubiquitous and race a social…

Medical research is held as a field for education to emulate. Education researchers have been urged to adopt randomized controlled trials, a more "scientific" research method believed to have resulted in the advances in medicine. But a much more important lesson education needs to borrow from medicine has been ignored. That is the study…

Video ethics in educational research involving children is a recent topic that has arisen since the increase in the use of visual mediums in research (such as photovoice and video) especially with the development of new and ubiquitous internet technologies and social media. This paper emerged as an expressed concerned by a group of scholars…

Meta-analyses often include only a small number of studies ([less than or equal to]5). Estimating between-study heterogeneity is difficult in this situation. An inaccurate estimation of heterogeneity can result in biased effect estimates and too narrow confidence intervals. The beta-binominal model has shown good statistical properties for…

Background: Multivariate meta-analysis (MVMA) jointly synthesizes effects for multiple correlated outcomes. The MVMA model is potentially more difficult and time-consuming to apply than univariate models, so if its use makes little difference to parameter estimates, it could be argued that it is redundant. Methods: We assessed the applicability…

Network meta-analysis (NMA) uses both direct and indirect evidence to compare the efficacy and harm between several treatments. Structural equation modeling (SEM) is a statistical method that investigates relations among observed and latent variables. Previous studies have shown that the contrast-based Lu-Ades model for NMA can be implemented in…

School-based research presents ethical challenges, especially with respect to informed consent. The manner in which pupils and their parents respond to an invitation to participate in research is likely to depend on several factors, including the level of trust between them and the researchers. This paper describes our recruitment and consent…