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Piepho, Hans-Peter; Madden, Laurence V. – Research Synthesis Methods, 2022
Network meta-analysis is a popular method to synthesize the information obtained in a systematic review of studies (e.g., randomized clinical trials) involving subsets of multiple treatments of interest. The dominant method of analysis employs within-study information on treatment contrasts and integrates this over a network of studies. One…
Descriptors: Medical Research, Meta Analysis, Networks, Drug Therapy
Meadows, Meredith L.; Suiter, Sarah V.; Sealy, Linda J.; Marshall, Dana R.; Whalen, Margaret M.; Adunyah, Samuel E. – CBE - Life Sciences Education, 2022
This study examined longitudinal education and career outcomes of the Meharry-Vanderbilt-Tennessee State University Cancer Partnership, the longest-running National Cancer Institute (NCI) Comprehensive Partnerships in Advancing Cancer Health Equity (CPACHE) program site in the United States. Degree completion rates were calculated and progression…
Descriptors: College Students, Oncology, Academic Achievement, Outcomes of Education
Reza Hosseini Ghomi; Sarah Holden; Aaron Ong; Akanksha Bawa; Ali Rafiq; Aparna Hariprasad; Christian Buensuceso; Emily Nguyen; Enoch Chung; Goda Lajauskaite; Hirali Kadakia; John Kim; Kaylani Tam; Kendra Leete; Kielan Lemoine-Kowalski; Kimmie Bacon; Lana Shamdeen; Nadav Brumer; Nikolai Liang; Yasmin Byott; David Atkins; John Neumaier – European Educational Researcher, 2019
Since the mid-1990s, the US has seen a decline in research activities in medical education and academic health care centers. Our goal was to offer a multi-disciplinary experience for undergraduates to participate in a practical, hands-on research experience to increase the likelihood of entering STEM research careers. The authors structured a…
Descriptors: Medical Education, Teaching Methods, Medical Research, Clinical Experience
van Dulmen, Tim H. H.; Visser, Talitha C.; Pepin, Birgit; McKenney, Susan – Research in Science & Technological Education, 2023
Background: Although cutting-edge chemistry research can be an interesting and motivating context for students in pre-university education, few characteristics of supportive and effective learning materials based on such contexts are available. Purpose: In this study we investigated the design, implementation, and evaluation of context-based…
Descriptors: Chemistry, Science Instruction, Material Development, Instructional Materials
Vetrovec, Logan; Massey, Anne; Santen, Sally A.; Edwards, Cherie; Kreutzer, Kathleen O'Kane; Harris, Kevin – Metropolitan Universities, 2022
Academic health centers (AHC) both contribute to and are influenced by the communities they serve. As part of a central commitment to improving human health, there is a need for AHCs to acknowledge their history related to race and racism, the resulting impact on current health disparities, and the disparate treatment of racial and minoritized…
Descriptors: Health Services, Medical Services, Medical Schools, Clinics
van Zundert, Camiel H. J.; Miocevic, Milica – Research Synthesis Methods, 2020
Synthesizing findings about the indirect (mediated) effect plays an important role in determining the mechanism through which variables affect one another. This simulation study compared six methods for synthesizing indirect effects: correlation-based MASEM, parameter-based MASEM, marginal likelihood synthesis, an adjustment to marginal likelihood…
Descriptors: Correlation, Comparative Analysis, Meta Analysis, Bayesian Statistics
Papadimitropoulou, Katerina; Stijnen, Theo; Riley, Richard D.; Dekkers, Olaf M.; Cessie, Saskia – Research Synthesis Methods, 2020
Meta-analysis of individual participant data (IPD) is considered the "gold-standard" for synthesizing clinical study evidence. However, gaining access to IPD can be a laborious task (if possible at all) and in practice only summary (aggregate) data are commonly available. In this work we focus on meta-analytic approaches of comparative…
Descriptors: Meta Analysis, Correlation, Scores, Outcomes of Treatment
Song, Yue; Sun, Feng; Redline, Susan; Wang, Rui – Research Synthesis Methods, 2020
Meta-analyses of clinical trials typically focus on one outcome at a time. However, treatment decision-making depends on an overall assessment of outcomes balancing benefit in various domains and potential risks. This calls for meta-analysis methods for combined outcomes that encompass information from different domains. When individual patient…
Descriptors: Meta Analysis, Patients, Data, Outcomes of Treatment
Li, Jiao; Gao, Furong; Jin, Caixia; Shi, Xiujuan; Zhang, Chen; Jia, Song; Xu, Jie; Lv, Lixia; Yang, Wenzhuo; Xu, Lei – Biochemistry and Molecular Biology Education, 2020
In teaching of experiments for medical students, by using the isolation of mononuclear cells and identification of B lymphocytes, an experiment was developed that integrated biochemistry, cytology, and immunology techniques, from which the students performed a series of operations including spleen separation, isolating mononuclear cells, and…
Descriptors: Cytology, Medical Students, Teaching Methods, Laboratory Experiments
Mackworth-Young, Charles – Journal of Research Administration, 2021
Background: The peer review of clinical research projects is an essential step in project preparation. While some projects undergo rigorous review by grant-giving organizations, this does not apply to all clinical research. In many cases, peer review, if undertaken at all, is not rigorous, fully independent, or timely. Depending on their…
Descriptors: Peer Evaluation, Medical Research, Research Projects, Ethics
Gomez-Jones, Tashaé; Kao, Robert M. – American Biology Teacher, 2021
Over the past decade, the development of three-dimensional mammalian cell organization--called human organoids--from stem cells has provided a framework for future clinical therapies. As human organoid research progresses, we also need to keep in mind the cross-cultural and ethical dimensions of human organoids research. Our review article aims to…
Descriptors: Ethics, Donors, Human Body, Cytology
Loretta Gasparini; Shaun Ziegenfusz; Natalie Turner; Suze Leitão; Michelle C. St Clair; Emily Jackson – International Journal of Language & Communication Disorders, 2025
Background: Eighty-five percent of medical research goes to waste, partly because it is not appropriately communicated to stakeholders. This represents a critical issue for the research community, especially because individuals who are impacted by research should be able to readily access that research. Making research findings accessible to key…
Descriptors: Language Impairments, Information Dissemination, Medical Research, Access to Information
Hoyer, Annika; Kuss, Oliver – Research Synthesis Methods, 2019
Diagnostic test accuracy studies frequently report on sensitivities and specificities for more than one threshold of the diagnostic test under study. Although it is obvious that the information from all thresholds should be used for a meta-analysis, in practice, frequently, only a single pair of sensitivity and specificity is selected. To overcome…
Descriptors: Meta Analysis, Diagnostic Tests, Correlation, Intervals
Simashkova, Natalya V.; Boksha, Irina S.; Klyushnik, Tatyana P.; Iakupova, Lubov' P.; Ivanov, Mikhail V.; Mukaetova-Ladinska, Elizabeta B. – Journal of Autism and Developmental Disorders, 2019
The study describes the latest recommended and adopted clinical and management practice for children and adults with autistic spectrum disorder (ASD) in Russia and discusses the most recent research work by Russian clinicians and neuroscientists in the field. The study also presents data from the first epidemiological studies on ASD prevalence and…
Descriptors: Foreign Countries, Clinical Diagnosis, Autism, Pervasive Developmental Disorders
Christofides, Emily; Stroud, Karla; Tullis, Diana Elizabeth; O'Doherty, Kieran C. – Research Ethics, 2019
The practice of communicating research findings to participants has been identified as important in the research ethics literature, but little research has examined empirically how this occurs and what research participants' views are in this regard. We interviewed 21 adults with cystic fibrosis who had previously participated in research and 2…
Descriptors: Genetic Disorders, Medical Research, Information Dissemination, Ethics