In a study of style of learning and thinking (hemisphericity) as it relates to scores on creativity tests, 28 graduate students were studied. (Author/PHR)

Describes the use of brain models to connect the microscopic level accessible by molecular and cellular techniques with the systems level accessible by the study of behavior. Discusses classes of brain models, and specific examples of such models. Evaluates the strengths and weaknesses of using brain modelling to understand human brain function.…

A questionnaire was developed and administered to 30 young children with autism and a control group to explore sensory hyper- and hypo-sensitivities. Significant differences were found between groups across all (auditory, tactile, visual, gustatory, and vestibular) domains. Findings are interpreted within the framework of theory of mind and joint…

This article reviews competing theories of semantic organization in the brain, including modular models, unitary models, and the matrix theory, and provides supporting and refuting evidence for each, incorporating examples from the imaging literature. The literature does provide some support for distinct neural substrates that process specific…

This review explores the cellular pathology associated with traumatic brain injury (TBI) and its relation to neurobehavioral outcomes, the relationship of brain imaging findings to underlying pathology, brain imaging techniques, various image analysis procedures and how they relate to neuropsychological testing, and the importance of brain imaging…

Forty children (ages 7-11) referred for evaluation of learning problems, who had normal scores on measures of academic achievement, were compared to 81 similarly referred children who had scored low. Children with normal achievement scores had higher IQs and better decoding skills, however, the two groups showed similar neuropsychological…

Notes that current research on early brain development emphasizes early care and education. Cautions educators to interpret and correctly translate this information into appropriate, effective child care and early education practices. Highlights pros and cons of research findings in: (1) child development; (2) special needs intervention; (3) care…

The efficacy of antiepileptic drugs (AEDs) and psychotropic medications in children with autism is limited to the treatment of seizures or to specific behaviors such as irritability, impulsivity, hyperactivity, repetitive behaviors, or aggression. The reliability and value of the available data--to determine the efficacy of these medications in…

Music, as language, is a universal human trait. Throughout human history and across all cultures, individuals have produced and enjoyed music. Despite its ubiquity, music is rarely studied as a basic and distinct cognitive faculty. However, recent evidence suggests that music might well be distinct from other cognitive functions, in being…

In two experiments, the time course of the expression of fear in trace (hippocampus-dependent) versus delay (hippocampus-independent) conditioning was characterized with a high degree of temporal specificity using fear-potentiated startle. In experiment 1, groups of rats were given delay fear conditioning or trace fear conditioning with a 3- or…

The polysialylated neural cell adhesion molecule (PSA-NCAM) has been implicated in activity-dependent synaptic remodeling and memory formation. Here, we questioned whether training-induced modulation of PSA-NCAM expression might be related to individual differences in spatial learning abilities. At 12 h posttraining, immunohistochemical analyses…

It is well established that the cerebellum and its associated circuitry are essential for classical conditioning of the eyeblink response and other discrete motor responses (e.g., limb flexion, head turn, etc.) learned with an aversive unconditioned stimulus (US). However, brain mechanisms underlying extinction of these responses are still…

Motor learning in the vestibulo-ocular reflex (VOR) and eyeblink conditioning use similar neural circuitry, and they may use similar cellular plasticity mechanisms. Classically conditioned eyeblink responses undergo extinction after prolonged exposure to the conditioned stimulus in the absence of the unconditioned stimulus. We investigated the…

Neural networks are applied to a theoretical subject in developmental psychology: modeling developmental transitions. Two issues that are involved will be discussed: discontinuities and acquiring qualitatively new knowledge. We will argue that by the appearance of a bifurcation, a neural network can show discontinuities and may acquire…

Inflammation during the perinatal period has become a recognized risk factor for developmental brain injuries over the past decade or more. To fully understand the relationship between inflammation and brain development, a comprehensive knowledge about the immune system within the brain is essential. Microglia are resident immune cells within the…