Every year, the Rainbow Round Table Committee from the American Library Association (ALA) selects quality lesbian, gay, bisexual, transgender, queer/questioning, intersex, and asexual+ (LGBTQIA+) books for the ALA's Rainbow Book List. The committee evaluated approximately 450 titles published in the United States and Canada between July 1, 2020, and December 31, 2021, and selected 122 titles for children and young adults for the 2022 Rainbow Book List, the 15th year the list has been compiled. This article presents annotiations of the 16 picture books that have been organized according to five different categories: (1) significant figures and role models; (2) family and family dynamics; (3) body positivity and gender identity; (4) language; and (5) special events and simple daily lives.